[HTML][HTML] Immunopathogenesis and treatment of cytokine storm in COVID-19

JS Kim, JY Lee, JW Yang, KH Lee, M Effenberger… - Theranostics, 2021 - ncbi.nlm.nih.gov
Abstract Severe coronavirus disease 2019 (COVID-19) is characterized by systemic hyper-
inflammation, acute respiratory distress syndrome, and multiple organ failure. Cytokine …

COVID-19: Immunology and treatment options

S Felsenstein, JA Herbert, PS McNamara… - Clinical …, 2020 - Elsevier
The novel coronavirus SARS-CoV2 causes COVID-19, a pandemic threatening millions. As
protective immunity does not exist in humans and the virus is capable of escaping innate …

[HTML][HTML] Calming the cytokine storm in COVID-19

RQ Cron, R Caricchio, WW Chatham - Nature medicine, 2021 - nature.com
Calming the cytokine storm in COVID-19 | Nature Medicine Skip to main content Thank you for
visiting nature.com. You are using a browser version with limited support for CSS. To obtain the …

A possible role for B cells in COVID-19? Lesson from patients with agammaglobulinemia

I Quinti, V Lougaris, C Milito, F Cinetto… - Journal of Allergy and …, 2020 - jacionline.org
To the Editor: An epidemic of coronavirus SARS-CoV-2 has become the focus of scientific
attention. 1 The high infectivity of SARS-CoV-2 and rapid rise in the number of patients …

[HTML][HTML] COVID-19-associated hyperinflammation and escalation of patient care: a retrospective longitudinal cohort study

JJ Manson, C Crooks, M Naja, A Ledlie… - The Lancet …, 2020 - thelancet.com
Background A subset of patients with severe COVID-19 develop a hyperinflammatory
syndrome, which might contribute to morbidity and mortality. This study explores a specific …

Deciphering the COVID‐19 cytokine storm: systematic review and meta‐analysis

R Mulchandani, T Lyngdoh… - European journal of …, 2021 - Wiley Online Library
Introduction The coronavirus pandemic has affected more than 20 million people so far.
Elevated cytokines and suppressed immune responses have been hypothesized to set off a …

COVID-19 associated multisystem inflammatory syndrome in children (MIS-C) guidelines; a Western New York approach

TR Hennon, MD Penque, R Abdul-Aziz… - Progress in pediatric …, 2020 - Elsevier
COVID-19, a severe viral respiratory infection caused by SARS-CoV-2, affects all age
groups, yet it is more severe in elderly and individuals with co-morbidities. Recently, a …

Weathering the COVID-19 storm: lessons from hematologic cytokine syndromes

JT England, A Abdulla, CM Biggs, AYY Lee, KA Hay… - Blood Reviews, 2021 - Elsevier
A subset of patients with severe COVID-19 develop profound inflammation and multi-organ
dysfunction consistent with a “Cytokine Storm Syndrome”(CSS). In this review we compare …

[HTML][HTML] Multisystem inflammatory syndrome in children (MIS-C), a post-viral myocarditis and systemic vasculitis—a critical review of its pathogenesis and treatment

JC McMurray, JW May, MW Cunningham… - Frontiers in …, 2020 - frontiersin.org
MIS-C is a newly defined post-viral myocarditis and inflammatory vasculopathy of children
following COVID-19 infection. This review summarizes the literature on diagnosis …

[HTML][HTML] Severe covid-19

DA Berlin, RM Gulick, FJ Martinez - New England Journal of …, 2020 - Mass Medical Soc
Key Clinical Points Evaluation and Management of Severe Covid-19 Patients with severe
coronavirus disease 2019 (Covid-19) may become critically ill with acute respiratory distress …