In late 2020, after circulating for almost a year in the human population, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibited a major step change in its …

The current coronavirus disease 2019 (COVID-19) pandemic is the first to apply whole-
genome sequencing near to real time, with over 2 million severe acute respiratory syndrome …

Abstract Omicron BA. 2.86 subvariant differs from Omicron BA. 2 as well as recently
circulating variants by over 30 mutations in the spike protein alone. Here we report on the …

Anosmia, the loss of smell, is a common and often the sole symptom of COVID-19. The onset
of the sequence of pathobiological events leading to olfactory dysfunction remains obscure …

Abstract SARS-CoV-2, like other coronaviruses, builds a membrane-bound replication
organelle to enable RNA replication. The SARS-CoV-2 replication organelle is composed of …

Tracking SARS-CoV-2 genetic diversity is strongly indicated because diversifying selection
may lead to the emergence of novel variants resistant to naturally acquired or vaccine …

The spike protein (S) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
directs infection of the lungs and other tissues following its binding to the angiotensin …

SARS-CoV-2 variants may threaten the effectiveness of vaccines and antivirals to mitigate
serious COVID-19 disease. This is of most concern in clinically vulnerable groups such as …

The independent emergence late in 2020 of the B. 1.1. 7, B. 1.351, and P. 1 lineages of
SARS-CoV-2 prompted renewed concerns about the evolutionary capacity of this virus to …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) variants govern
transmissibility, responsiveness to vaccination, and disease severity. In a screen for new …