Aptamer-based diagnostic and therapeutic approaches for animal viruses: A review

Z Chen, Q Sun, Y Yang, X Nie, W Xiang, Y Ren… - International Journal of …, 2023 - Elsevier
Animal diseases often have significant consequences due to the unclear and time-
consuming diagnosis process. Furthermore, the emergence of new viral infections and drug …

Neutrophil extracellular traps and their implications in airway inflammatory diseases

N Xuan, J Zhao, Z Kang, W Cui, B Tian - Frontiers in Medicine, 2024 - frontiersin.org
Neutrophil extracellular traps (NETs) are essential for immune defense and have been
increasingly recognized for their role in infection and inflammation. In the context of airway …

Impact of Alteplase on Mortality in Critically Ill Patients with COVID-19 and Pulmonary Embolism

OV Oliynyk, M Rorat, SO Solyarik, VA Lukianchuk… - Viruses, 2023 - mdpi.com
COVID-19 is an independent risk factor for pulmonary embolism (PE). Little is known about
alteplase therapy in this patient group. A retrospective study analyzed 74 patients with PE …

Emerging evidence of microbial infection in causing systematic immune vasculitis in Kawasaki disease

W Wang, L Zhu, X Li, Z Liu, H Lv, G Qian - Frontiers in Microbiology, 2023 - frontiersin.org
Kawasaki disease (KD) is a systematic vasculitis that is often complicated by coronary artery
lesions and is a leading cause of acquired heart disease in developed countries. Previous …

[HTML][HTML] Antibody drugs targeting SARS-CoV-2: Time for a rethink?

L Liang, B Wang, Q Zhang, S Zhang, S Zhang - Biomedicine & …, 2024 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) heavily burdens human health. Multiple …

ACE2 improves endothelial cell function and reduces acute lung injury by downregulating FAK expression

Y He, B Gang, M Zhang, Y Bai, Z Wan, J Pan… - International …, 2024 - Elsevier
Endothelial cell (EC) barrier dysfunction and increased adhesion of immune inflammatory
cells to ECs crucially contribute to acute lung injury (ALI). Angiotensin-converting enzyme 2 …

The Dual-Targeted Fusion Inhibitor Clofazimine Binds to the S2 Segment of the SARS-CoV-2 Spike Protein

MR Freidel, PA Vakhariya, SK Sardarni, RS Armen - Viruses, 2024 - mdpi.com
Clofazimine and Arbidol have both been reported to be effective in vitro SARS-CoV-2 fusion
inhibitors. Both are promising drugs that have been repurposed for the treatment of COVID …

The possible mechanism and research progress of ACE2 involved in cardiovascular injury caused by COVID-19: a review

D Luo, M Bai, W Zhang, J Wang - Frontiers in Cardiovascular …, 2024 - frontiersin.org
ACE2 is the earliest receptor discovered to mediate the entry of SARS-CoV-2. In addition to
the receptor, it also participates in complex pathological and physiological processes …

Biomarkers in COVID-19 pandemic: implications for acute phase assessment and chronic management

F Bianchi - 2024 - usiena-air.unisi.it
COVID-19 is the syndrome caused by SARS-CoV-2 infection. Severe phenotypes seem to
be caused by a “cytokines storm” and pneumonia is one of the most important clinical …

Emerging SARS-CoV-2 Variants and Their Impact on Immune Evasion and Vaccine-Induced Immunity

DL Gupta, DN Rao - 2023 - preprints.org
The newly emerged variants of SARS-CoV-2 created a potential threat among societies and
highlighted one of the significant concerns in facing the pandemic. SARS-CoV-2 variants …