Recently, it has been shown that release of cytochrome c from the mitochondria to the
cytosol is required for activation of the caspase-3-dependent cascade in apoptosis, and also …

Since the 1950s, when serotonin (5-HT) was discovered in the mammalian central nervous
system (CNS), an enormous amount of experimental evidence has revealed the pivotal role …

PURPOSE To evaluate the safety and efficacy of risperidone in patients with Parkinson's
disease (PD) who are experiencing significant dopamine‐induced psychosis. PATIENTS …

Parkinson's disease (PD) is a progressive, neurodegenerative disorder which involves the
loss of dopaminergic neurons of the substantia nigra pars compacta. Current therapy is …

Nanotechnology is an emerging field that is useful for various purposes. Numerous
neurological disorders, such as Parkinson's disease (PD), Alzheimer's disease (AD), stroke …

L-Dopa is the mainstay of Parkinson's disease therapy; this drug is usually administered
orally, but it is extensively metabolized in the gastrointestinal tract, so that relatively little …

The limbic system includes the complex of brain centres, nuclei and connections that
provide the anatomical substrate for emotions. Although the presence of small amounts of …

A semi-automated alumina-based extraction method for the determination of l-dopa and
dopamine in plasma using liquid chromatography/mass spectrometry was validated. The …

Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor control
deficits, which is associated with the loss of striatal dopaminergic neurons from the …

Background: When levodopa therapy is used in Parkinson's disease, degradation of the
drug in the peripheral nervous system is associated with dyskinesias and motor fluctuations …