Power of integrating PBPK with PBBM (PBPK-BM): a single model predicting food effect, gender impact, drug-drug interactions and bioequivalence in fasting & fed …

R Boddu, S Kollipara, G Vijaywargi, T Ahmed - Xenobiotica, 2023 - Taylor & Francis
Over the past few years, PBPK and PBBM modelling have proven their significance in drug
development. PBPK modelling is traditionally used to predict drug-drug interactions …

Research Landscape of Physiologically Based Pharmacokinetic Model Utilization in Different Fields: A Bibliometric Analysis (1999–2023)

X Wang, J Wu, H Ye, X Zhao, S Zhu - Pharmaceutical Research, 2024 - Springer
Purpose The physiologically based pharmacokinetic (PBPK) modeling has received
increasing attention owing to its excellent predictive abilities. However, there has been no …

[PDF][PDF] Early Kidney and liver Dysfunction Associated with Exposure to Crude Oil in Al-Ahdab field

NN Alqurashy, ZZ Al-Mamoori, SMA Alkadhimi - Wasit Journal for Pure …, 2023 - iasj.net
Although the detrimental effects of crude oil on many types of plants and animals have been
broadly studied, not enough research has been done on how exposure to oil affects human …

Linking in vitro–in vivo extrapolations with physiologically based modeling to inform drug and formulation development

R Cristofoletti… - Biopharmaceutics & Drug …, 2023 - Wiley Online Library
Research activities in RC lab at the Center for Pharmacometrics and Systems Pharmacology
(CPSP) at the University of Florida are partially funded by pharmaceutical companies. ARH …