Ferroptosis in gastrointestinal cancer: from mechanisms to implications

R Zhang, R Kang, D Tang - Cancer Letters, 2023 - Elsevier
Ferroptosis is a form of regulated cell death that is initiated by excessive lipid peroxidation
that results in plasma membrane damage and the release of damage-associated molecular …

[HTML][HTML] Mitochondria related cell death modalities and disease

C Tian, Y Liu, Z Li, P Zhu, M Zhao - Frontiers in Cell and …, 2022 - frontiersin.org
Mitochondria are well known as the centre of energy metabolism in eukaryotic cells.
However, they can not only generate ATP through the tricarboxylic acid cycle and oxidative …

Nano-selenium protects grass carp hepatocytes against 4-tert-butylphenol-induced mitochondrial apoptosis and necroptosis via suppressing ROS-PARP1 axis

J Cui, M Qiu, Y Liu, Y Liu, Y Tang, X Teng… - Fish & Shellfish …, 2023 - Elsevier
tert-butylphenol (4-tBP) is a monomer widely used in the synthesis of industrial chemicals,
and posed a high risk to aquatic animals. Our study focused on toxic phenotype and …

A vanadium-based nanoplatform synergizing ferroptotic-like therapy with glucose metabolism intervention for enhanced Cancer Cell Death and Antitumor Immunity

Y Zhang, X Du, Z He, S Gao, L Ye, J Ji, X Yang… - ACS nano, 2023 - ACS Publications
Ferroptosis activation has been considered a mighty weapon for cancer treatment, and
growing attention is being paid to reinforcing tumor cells' sensitivity to ferroptosis. However …

[HTML][HTML] Melatonin alleviates acute sleep deprivation-induced memory loss in mice by suppressing hippocampal ferroptosis

X Wang, Z Wang, J Cao, Y Dong, Y Chen - Frontiers in pharmacology, 2021 - frontiersin.org
Objectives: Memory decline caused by insufficient sleep is a critical public health issues and
currently lacks effective treatments. This study objective was to explore alleviative effect of …

[HTML][HTML] System-level biological effects of extremely low-frequency electromagnetic fields: an in vivo experimental review

H Tian, H Zhu, C Gao, M Shi, D Yang, M Jin… - Frontiers in …, 2023 - frontiersin.org
During the past decades, the potential effects of extremely low-frequency electromagnetic
fields (ELF-EMFs) on human health have gained great interest all around the world. Though …

[HTML][HTML] Oxidative stress: a suitable therapeutic target for optic nerve diseases?

F Buonfiglio, EW Böhm, N Pfeiffer, A Gericke - Antioxidants, 2023 - mdpi.com
Optic nerve disorders encompass a wide spectrum of conditions characterized by the loss of
retinal ganglion cells (RGCs) and subsequent degeneration of the optic nerve. The etiology …

Genotoxic effects of electromagnetic field radiations from mobile phones

GC Jagetia - Environmental Research, 2022 - Elsevier
The use of wireless communication technology in mobile phones has revolutionized modern
telecommunication and mobile phones have become so popular that their number exceeds …

Targeting ferroptosis for lung diseases: exploring novel strategies in ferroptosis‐associated mechanisms

TL Ma, Y Zhou, C Wang, L Wang… - Oxidative medicine …, 2021 - Wiley Online Library
Ferroptosis is an iron‐dependent regulated necrosis characterized by the peroxidation
damage of lipid molecular containing unsaturated fatty acid long chain on the cell …

Serine-70 phosphorylated Bcl-2 prevents oxidative stress-induced DNA damage by modulating the mitochondrial redox metabolism

SJF Chong, K Iskandar, JXH Lai, J Qu… - Nucleic acids …, 2020 - academic.oup.com
Abstract Bcl-2 phosphorylation at serine-70 (S70pBcl2) confers resistance against drug-
induced apoptosis. Nevertheless, its specific mechanism in driving drug-resistance remains …