Background: Symptoms related to mood and anxiety disorders often present in childhood
and adolescence. Some of the genetic liability for mental disorders, and emotional and …

The past two decades have seen the advent and mass application of genome-wide
association studies (GWAS). The observation that complex phenotypes are polygenic has …

Striatal dopaminergic overactivity was hypothesized as the core pathophysiology of
schizophrenia. However, understanding structural alterations in striatum of schizophrenia …

The last decades of research in schizophrenia witnessed a shift of etiological speculation
from neurotransmitters to inflammation. However, identifying definite inflammatory effectors …

Background Bipolar disorder (BD) is a highly heritable psychiatric illness exhibiting
substantial correlation with intelligence. Methods To investigate the shared genetic …

Genetic pleiotropy is abundant across spatially distributed brain characteristics derived from
one neuroimaging modality (eg structural, functional or diffusion MRI). A better …

The present study examines two classes of behavior in probands with the 16p11. 2
duplication and deletion: repetitive behavior and psychosis spectrum behavior. It was …

Schizophrenia shares genetics with brain volume alterations | Nature Reviews Neurology Skip to
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An understanding of human brain individuality requires the integration of data on brain
organization across individuals, molecular and systems scales, as well as healthy and …

Uncovering the genetic architectures of brain morphology offers valuable insights into brain
development and disease. Genetic association studies of brain morphological phenotypes …