A large body of evidence generated in the last two and a half years addresses the roles of T cells in SARS-CoV-2 infection and following vaccination. Infection or vaccination induces …
Studies have demonstrated that at least 20% of individuals infected with SARS-CoV-2 remain asymptomatic,,–. Although most global efforts have focused on severe illness in …
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection of vaccinated individuals is increasingly common but rarely results in severe disease, likely due to the …
Since the onset of the coronavirus disease 2019 (COVID-19) pandemic, multiple severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants with increasing ability to …
SARS-CoV-2 breakthrough infection in vaccinees induces virus-specific nasal-resident CD8+ and CD4+ T cells of broad specificity | Journal of Experimental Medicine | Rockefeller …
The lungs are constantly exposed to inhaled debris, allergens, pollutants, commensal or pathogenic microorganisms, and respiratory viruses. As a result, innate and adaptive …
M Goncharov, D Bagaev, D Shcherbinin, I Zvyagin… - Nature …, 2022 - nature.com
In 2016, we started a community effort to gather and curate publicly available sequence data acquired from T cell receptor (TCRs) with defined antigen specificities, as well as …
T cells are a critical component of the response to SARS-CoV-2, but their kinetics after infection and vaccination are insufficiently understood. Using" spheromer" peptide-MHC …
C Cai, Y Gao, S Adamo, O Rivera-Ballesteros… - Science …, 2023 - science.org
T cells are critical for immune protection against severe COVID-19, but it has remained unclear whether repeated exposure to SARS-CoV-2 antigens delivered in the context of …