A synaptic perspective of fragile X syndrome and autism spectrum disorders

C Bagni, RS Zukin - Neuron, 2019 - cell.com
Altered synaptic structure and function is a major hallmark of fragile X syndrome (FXS),
autism spectrum disorders (ASDs), and other intellectual disabilities (IDs), which are …

Genetic contributions to autism spectrum disorder

A Havdahl, M Niarchou, A Starnawska… - Psychological …, 2021 - cambridge.org
Autism spectrum disorder (autism) is a heterogeneous group of neurodevelopmental
conditions characterized by early childhood-onset impairments in communication and social …

The neuropathology of autism: A systematic review of post-mortem studies of autism and related disorders

R Fetit, RF Hillary, DJ Price, SM Lawrie - Neuroscience & Biobehavioral …, 2021 - Elsevier
Post-mortem studies allow for the direct investigation of brain tissue in those with autism and
related disorders. Several review articles have focused on aspects of post-mortem …

The role of glutathione redox imbalance in autism spectrum disorder: a review

G Bjørklund, AA Tinkov, B Hosnedlová, R Kizek… - Free Radical Biology …, 2020 - Elsevier
The role of glutathione in autism spectrum disorder (ASD) is emerging as a major topic, due
to its role in the maintenance of the intracellular redox balance. Several studies have …

[HTML][HTML] Dissecting the heterogeneous cortical anatomy of autism spectrum disorder using normative models

M Zabihi, M Oldehinkel, T Wolfers, V Frouin… - Biological psychiatry …, 2019 - Elsevier
Background The neuroanatomical basis of autism spectrum disorder (ASD) has remained
elusive, mostly owing to high biological and clinical heterogeneity among diagnosed …

From many to one to many—the search for causes of psychiatric illness

KS Kendler - JAMA psychiatry, 2019 - jamanetwork.com
The search for the causes of medical and psychiatric disorders has gone through 3 historical
phases. First, up until the mid-19th century, causes of illness were anecdotally recorded from …

Cannabidiol as a suggested candidate for treatment of autism spectrum disorder

S Poleg, P Golubchik, D Offen, A Weizman - Progress in Neuro …, 2019 - Elsevier
Abstract Autism Spectrum Disorder (ASD) is characterized by persistent deficits in social
communication, restricted and repetitive patterns of behavior, interests, or activities and often …

Neuropsychopathology of autism spectrum disorder: complex interplay of genetic, epigenetic, and environmental factors

R Bhandari, JK Paliwal, A Kuhad - … food intervention and therapy for autism …, 2020 - Springer
Autism spectrum disorder (ASD) is a complex heterogeneous consortium of pervasive
development disorders (PDD) which ranges from atypical autism, autism, and Asperger …

Neural mechanisms underlying repetitive behaviors in rodent models of autism spectrum disorders

T Gandhi, CC Lee - Frontiers in cellular neuroscience, 2021 - frontiersin.org
Autism spectrum disorder (ASD) is comprised of several conditions characterized by
alterations in social interaction, communication, and repetitive behaviors. Genetic and …

Mouse population genetics phenocopies heterogeneity of human Chd8 haploinsufficiency

M Tabbaa, A Knoll, P Levitt - Neuron, 2023 - cell.com
Preclinical models of neurodevelopmental disorders typically use single inbred mouse
strains, which fail to capture the genetic diversity and symptom heterogeneity that is common …