Men with mutations in LHB, the gene encoding the beta subunit of luteinizing hormone
(LHB), have azoospermia with absent or few fetal Leydig cells. We report a mutation in LHB …

Male infertility can range from neurohormonal imbalances, reproductive tissue disruptions,
qualitative and quantitative deterioration of semen to sexual behavioral problems. The …

Background Male hormonal contraception has been an elusive goal. Administration of sex
steroids to men can shut off sperm production through effects on the pituitary and …

Many health problems are related to lifestyle and dietary factors. Increasing trend in
reproductive disorders observed in recent years may be associated at least in part with …

During adolescence, androgens are responsible for the development of secondary sexual
characteristics, pubertal growth, and the anabolic effects on bone and muscle mass …

As a protein kinase inhibitor, cantharidin (CTD) exhibits antitumor activities. However, CTD
is highly toxic, thereby limiting clinical applications. Moreover, relatively few studies have …

Intratesticular testosterone is vital for spermatogenesis, male fertility, and virility. Currently
the only method to assess levels of intratesticular testosterone is to perform testicular biopsy …

Arboviruses can cause a variety of clinical signs, including febrile illness, arthritis,
encephalitis, and hemorrhagic fever. The recent Zika epidemic highlighted the possibility …

Good-quality reproductive cells are essential for reproduction. Endocrine disruptors are
widely available in the environment and are known to have an adverse effect on …

In recent years a new picture of human sperm biology is emerging. It is now widely
recognized that sperm contain nuclear encoded mRNA, mitochondrial encoded RNA and …