Inflammatory bowel disease (IBD) is an immune-mediated disease of the intestinal tract, with
complex pathophysiology involving genetic, environmental, microbiome, immunological and …

Inflammatory bowel disease is characterized by defects in epithelial function and
dysregulated inflammatory signaling by lamina propria mononuclear cells including …

The gut microbiota plays a key role in host health and disease, particularly through their
interactions with the immune system. Intestinal homeostasis is dependent on the symbiotic …

Multiple sclerosis (MS) is a neuroimmunological disorder of the CNS with a strong heritable
component. The genetic architecture of MS susceptibility is well understood in populations of …

Inflammatory bowel disease (IBD) is characterized by chronic inflammation of the
gastrointestinal system. Omega-3 (ω3) fatty acids are polyunsaturated fatty acids (PUFAs) …

Abstract Background Perturbagen analysis of Crohn's disease (CD) ileal gene expression
data identified small molecules including eicosatetraynoic acid (ETYA), which may exert an …

Background Genome wide association studies (GWAS) have identified and validated more
than 200 genomic loci associated with the inflammatory bowel disease (IBD), although for …

Inflammatory bowel disease (IBD), with Crohn's disease and ulcerative colitis as main
subtypes, is a prototypical multifactorial disease with both genetic and environmental factors …

Research on the care of inflammatory bowel disease (IBD) patients has been primarily in
populations of European ancestry. However, the incidence of IBD, which comprises Crohn's …

Objective To describe racial inequities in pediatric inflammatory bowel disease care and
explore potential drivers. Methods We undertook a single-center, comparative cohort study …