Unveiling the future of metabolic medicine: omics technologies driving personalized solutions for precision treatment of metabolic disorders

S Singh, DK Sarma, V Verma, R Nagpal… - … and Biophysical Research …, 2023 - Elsevier
Metabolic disorders are increasingly prevalent worldwide, leading to high rates of morbidity
and mortality. The variety of metabolic illnesses can be addressed through personalized …

360-degree perspectives on obesity

M Cuciureanu, CC Caratașu, L Gabrielian… - Medicina, 2023 - mdpi.com
Alarming statistics show that the number of people affected by excessive weight has
surpassed 2 billion, representing approximately 30% of the world's population. The aim of …

Evaluation of pediatric epigenetic clocks across multiple tissues

F Fang, L Zhou, W Perng, CJ Marsit, AK Knight… - Clinical …, 2023 - Springer
Background Epigenetic clocks are promising tools for assessing biological age. We
assessed the accuracy of pediatric epigenetic clocks in gestational and chronological age …

Cold exposure protects against medial arterial calcification development via autophagy

FXZ Li, JJ Liu, F Xu, SK Shan, MH Zheng… - Journal of …, 2023 - Springer
Medial arterial calcification (MAC), a systemic vascular disease different from
atherosclerosis, is associated with an increased incidence of cardiovascular events. Several …

Emerging epigenetic insights into aging mechanisms and interventions

Z Wu, W Zhang, J Qu, GH Liu - Trends in Pharmacological Sciences, 2024 - cell.com
Epigenetic dysregulation emerges as a critical hallmark and driving force of aging. Although
still an evolving field with much to explore, it has rapidly gained significance by providing …

Protein neddylation and its role in health and diseases

S Zhang, Q Yu, Z Li, Y Zhao, Y Sun - Signal Transduction and Targeted …, 2024 - nature.com
NEDD8 (Neural precursor cell expressed developmentally downregulated protein 8) is an
ubiquitin-like protein that is covalently attached to a lysine residue of a protein substrate …

Classification, function, and advances in tsRNA in non-neoplastic diseases

L Zhang, J Liu, Y Hou - Cell Death & Disease, 2023 - nature.com
Abstract tRNA-derived small RNAs (tsRNAs) are non-coding small RNAs produced by
specific endonucleases following the processing and splicing of precursor or mature tRNAs …

The role of epigenetic control of mitochondrial (Dys) Function in MASLD onset and progression

V Caputo, G Tarantino, SJ Santini, G Fracassi… - Nutrients, 2023 - mdpi.com
Metabolic dysfunction-associated steatotic fatty liver disease (MASLD), a novel definition for
NAFLD, represents one of the most common causes of liver disease, and its incidence is …

Self-powered optical fiber biosensor integrated with enzymes for non-invasive glucose sensing

X Wen, X Yang, Z Ge, H Ma, R Wang, F Tian… - Biosensors and …, 2024 - Elsevier
To alleviate the discomfort associated with frequent blood glucose detection in diabetic
patients, a novel non-invasive tear glucose biosensor has been developed. This involved …

An update on potential molecular biomarkers of dietary phytochemicals targeting lung cancer interception and prevention

RM Peter, PJ Chou, A Shannar, K Patel, Y Pan… - Pharmaceutical …, 2023 - Springer
Since ancient times, dietary phytochemicals are known for their medicinal properties. They
are broadly classified into polyphenols, terpenoids, alkaloids, phytosterols, and organosulfur …