One of the remarkable features of eukaryotes is the nucleus, delimited by the nuclear
envelope (NE), a complex structure and home to the nuclear lamina and nuclear pore …

Glycosphingolipids (GSLs) are comprised of glycans (oligosaccharides) linked to a lipid
containing a sphingosine moiety. They are major membrane components in cells of most …

Malaria remains a significant global health priority despite all efforts to control the disease. In
2022, according to the World Health Organization (WHO), more than 249 million cases were …

Dolichols are isoprenoid end-products of the mevalonate and 2 C-methyl-D-erythritol-4-
phosphate pathways. The synthesis of dolichols is initiated with the addition of several …

This review aims to summarize the currently viable vaccine strategies including the
approved vaccines and the those in trials for next-generation malaria vaccines. Data on …

Novel Furopyridine and Furopyrimidine Compounds as PI4K Inhibitors for Treating Malaria
and Viral Infection Page 1 Novel Furopyridine and Furopyrimidine Compounds as PI4K …

Parasitic diseases, including malaria, leishmaniasis, and trypanosomiasis, continue to
plague populations worldwide, particularly in resource-limited settings and …

It is well-accepted that knowledge of a small molecule's target can accelerate optimization.
Although chemogenomic databases are helpful resources for predicting or finding …

Medical parasitology is a specialty of medicine that studies, diagnoses, as well as treats
parasitic illnesses in humans. Numerous parasites still require human microscopic testing …

Protozoan pathogens such as Plasmodium spp., Leishmania spp., Toxoplasma gondii, and
Trypanosoma spp. are often associated with high-mortality, acute and chronic diseases of …