Bioactive compounds from marine bacteria and fungi

A Debbab, AH Aly, WH Lin… - Microbial biotechnology, 2010 - Wiley Online Library
Marine bacteria and fungi are of considerable importance as new promising sources of a
huge number of biologically active products. Some of these marine species live in a stressful …

Advances in Aspergillus secondary metabolite research in the post-genomic era

JF Sanchez, AD Somoza, NP Keller… - Natural product reports, 2012 - pubs.rsc.org
Covering: 2005 to 2011 This review studies the impact of whole genome sequencing on
Aspergillus secondary metabolite research. There has been a proliferation of many new …

Diversity and Characterization of Endophytic Fungi Isolated From the Tropical Mangrove Species, Rhizophora mucronata, and Identification of Potential Antagonists Against the …

TNT Hamzah, SY Lee, A Hidayat, R Terhem… - Frontiers in …, 2018 - frontiersin.org
Rhizophora mucronata is an important ecosystem entity of the Malaysian mangrove forest.
Since the species grows in a harsh environment, any organism that is isolated from this …

Total synthesis of (+)-11, 11'-dideoxyverticillin A

J Kim, JA Ashenhurst, M Movassaghi - Science, 2009 - science.org
The fungal metabolite (+)-11, 11′-dideoxyverticillin A, a cytotoxic alkaloid isolated from a
marine Penicillium sp., belongs to a fascinating family of densely functionalized …

Biogenetically-inspired total synthesis of epidithiodiketopiperazines and related alkaloids

J Kim, M Movassaghi - Accounts of Chemical Research, 2015 - ACS Publications
Conspectus Natural products chemistry has historically been the prime arena for the
discovery of new chemical transformations and the fountain of insights into key biological …

Transcriptional regulatory elements in fungal secondary metabolism

W Yin, NP Keller - The Journal of Microbiology, 2011 - Springer
Filamentous fungi produce a variety of secondary metabolites of diverse beneficial and
detrimental activities to humankind. The genes required for a given secondary metabolite …

Self-Protection against Gliotoxin—A Component of the Gliotoxin Biosynthetic Cluster, GliT, Completely Protects Aspergillus fumigatus Against Exogenous Gliotoxin

M Schrettl, S Carberry, K Kavanagh, H Haas… - PLoS …, 2010 - journals.plos.org
Gliotoxin, and other related molecules, are encoded by multi-gene clusters and
biosynthesized by fungi using non-ribosomal biosynthetic mechanisms. Almost universally …

Epidithiodioxopiperazines. occurrence, synthesis and biogenesis

TR Welch, RM Williams - Natural product reports, 2014 - pubs.rsc.org
Covering: 1936 to 2013 Epidithiodioxopiperazine alkaloids possess an astonishing array of
molecular architecture and generally exhibit potent biological activity. Nearly twenty distinct …

Biogenetically inspired syntheses of alkaloid natural products

J Kim, M Movassaghi - Chemical Society Reviews, 2009 - pubs.rsc.org
Since the synthesis of tropinone in the early 20th century, generations of chemists have
looked to nature for inspiration in developing elegant syntheses of natural products …

Diketopiperazines from marine organisms

R Huang, X Zhou, T Xu, X Yang… - Chemistry & Biodiversity, 2010 - Wiley Online Library
Diketopiperazines (DKPs), which are cyclic dipeptides, have been detected in a variety of
natural resources. Recently, the interest in these compounds increased significantly …