Impaired dendritic cell functions in lung cancer: a review of recent advances and future perspectives

JB Wang, X Huang, FR Li - Cancer communications, 2019 - Springer
Lung cancer is the leading cause of cancer mortality worldwide. Dendritic cells (DCs) are the
key factors providing protective immunity against lung tumors and clinical trials have proven …

The dendritic cell and human cancer vaccines

RM Dallal, MT Lotze - Current opinion in immunology, 2000 - Elsevier
Over the past ten years, the identification of the critical role that dendritic cells (DCs) play in
stimulating a specific immune response has led to their use in cancer and HIV therapy …

Differential tumor surveillance by natural killer (NK) and NKT cells

MJ Smyth, KYT Thia, SEA Street, E Cretney… - The Journal of …, 2000 - rupress.org
Natural tumor surveillance capabilities of the host were investigated in six different mouse
tumor models where endogenous interleukin (IL)-12 does or does not dictate the efficiency …

The early progenitors of mouse dendritic cells and plasmacytoid predendritic cells are within the bone marrow hemopoietic precursors expressing Flt3

A D'Amico, L Wu - The Journal of experimental medicine, 2003 - rupress.org
Flt3 ligand (Flt3L) is a growth factor for hemopoietic progenitors and can promote the
expansion of both conventional dendritic cells (DCs) and plasmacytoid predendritic cells (p …

Infection of human dendritic cells by dengue virus causes cell maturation and cytokine production

LJ Ho, JJ Wang, MF Shaio, CL Kao… - The Journal of …, 2001 - journals.aai.org
Dengue virus (DV) infection is a major problem in public health. It can cause fatal diseases
such as Dengue hemorrhagic fever and Dengue shock syndrome. Dendritic cells (DC) are …

Preoperative mobilization of circulating dendritic cells by Flt3 ligand administration to patients with metastatic colon cancer

MA Morse, S Nair, M Fernandez-Casal… - Journal of Clinical …, 2000 - ascopubs.org
PURPOSE: To evaluate preoperative dendritic cell (DC) mobilization and tumor infiltration
after administration of Flt3 ligand (Flt3L) to patients with metastatic colon cancer. PATIENTS …

Effects of administration of progenipoietin 1, Flt-3 ligand, granulocyte colony-stimulating factor, and pegylated granulocyte-macrophage colony-stimulating factor on …

M O'Keeffe, H Hochrein, D Vremec… - Blood, The Journal …, 2002 - ashpublications.org
We studied the effects of administration of several cytokines, including progenipoietin-1
(ProGP-1), Flt-3 ligand (FL), granulocyte colony-stimulating factor (G-CSF), and granulocyte …

Effects of antigen and genetic adjuvants on immune responses to human immunodeficiency virus DNA vaccines in mice

AC Moore, W Kong, BK Chakrabarti… - Journal of virology, 2002 - Am Soc Microbiol
The effects of genetic adjuvants on humoral and cell-mediated immunity to two human
immunodeficiency virus antigens, Env and Nef, have been examined in mice. Despite …

Inhibition of FLT3 signaling targets DCs to ameliorate autoimmune disease

KA Whartenby, PA Calabresi… - Proceedings of the …, 2005 - National Acad Sciences
Autoimmune diseases often result from inappropriate or unregulated activation of
autoreactive T cells. Traditional approaches to treatment of autoimmune diseases through …

The impact of imiquimod, a Toll-like receptor-7 ligand (TLR7L), on the immunogenicity of melanoma peptide vaccination with adjuvant Flt3 ligand

M Shackleton, ID Davis, W Hopkins, H Jackson… - Cancer Immunity, 2004 - AACR
Dendritic cells (DCs) show promise as adjuvants in anticancer immunotherapeutic
strategies. Flt3 ligand (FL) is a hematopoietic growth factor that increases the number of …