Human diet‐derived polyphenolic compounds and hepatic diseases: From therapeutic mechanisms to clinical utilization

Q Hu, W Zhang, F Wei, M Huang, M Shu… - Phytotherapy …, 2024 - Wiley Online Library
This review focuses on the potential ameliorative effects of polyphenolic compounds derived
from human diet on hepatic diseases. It discusses the molecular mechanisms and recent …

[HTML][HTML] Mechanism and recent updates on insulin-related disorders

S Kumar, S Senapati, N Bhattacharya… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Insulin, a small protein with 51 amino acids synthesized by pancreatic β-cells, is crucial to
sustain glucose homeostasis at biochemical and molecular levels. Numerous metabolic …

Green synthesis and characterization of silicate nanostructures coated with Pluronic F127/gelatin for triggered drug delivery in tumor microenvironments

NV Mdlovu, RS Juang, MT Weng, KS Lin - International Journal of …, 2023 - Elsevier
Thermo-/pH-sensitive nanocomposites based on mesoporous silicate MCM-41 (MSNCs)
derived from rice husk ash were synthesized and characterized. MSNCs were coated with …

Protective role of hesperetin in sorafenib-induced hepato-and neurotoxicity in mice via modulating apoptotic pathways and mitochondrial reprogramming

D Zaafar, HMA Khalil, R Elnaggar, DZ Saad… - Life Sciences, 2024 - Elsevier
Introduction Sorafenib, an FDA-approved standard chemotherapy for advanced
hepatocellular carcinoma, is associated with numerous adverse effects that significantly …

[HTML][HTML] Molecular targeted therapies for cutaneous squamous cell carcinoma: recent developments and clinical implications

H Singh, H Chopra, I Singh, S Mohanto, MG Ahmed… - EXCLI …, 2024 - ncbi.nlm.nih.gov
Abstract Cutaneous Squamous Cell Carcinoma (cSCC) is a common and potentially fatal
type of skin cancer that poses a significant threat to public health and has a high prevalence …

Comparative bioactivity analysis of hydro-methanolic extracts of root, leaf, and inflorescence of Tupistra nutans Wall. ex Lindl: An in vitro study on antioxidant and anti …

AC Roy, A Prasad, S Singh, K Priya, I Ghosh - Biocatalysis and Agricultural …, 2023 - Elsevier
Tupistra nutans, native to the Eastern Himalayas, is traditionally used as vegetables and in
manaand pressure. Despite being a medicinal agricultural plant, no in-depth antioxidant and …

[HTML][HTML] Natural compounds targeting YAP/TAZ axis in cancer: Current state of art and challenges

A Kumar, B BharathwajChetty, MK Manickasamy… - Pharmacological …, 2024 - Elsevier
Cancer has become a burgeoning global healthcare concern marked by its exponential
growth and significant economic ramifications. Though advancements in the treatment …

[HTML][HTML] Key oncogenic signaling pathways affecting tumor-infiltrating lymphocytes infiltration in hepatocellular carcinoma: basic principles and recent advances

X Wang, Z Yuan, Z Li, X He, Y Zhang, X Wang… - Frontiers in …, 2024 - frontiersin.org
The incidence of hepatocellular carcinoma (HCC) ranks first among primary liver cancers,
and its mortality rate exhibits a consistent annual increase. The treatment of HCC has …

[HTML][HTML] Integrative analysis of the molecular signature of target genes involved in the antitumor effects of cantharidin on hepatocellular carcinoma

J Yan, Y Gao, X Deng, H Wang, G Shi - BMC cancer, 2023 - Springer
Background Cantharidin (CTD) is the active ingredient of Chinese medicine, which has
been traditionally used in multiple cancers treatment, especially in hepatocellular carcinoma …

Protein profiles reveal MSH6/MSH2 as a potential biomarker for hepatocellular carcinoma with microvascular invasion

S Hong, J Zhang, S Liu, Q Jin, J Li, A Xia… - Hepatology …, 2024 - Wiley Online Library
Aim Microvascular invasion (MVI) is an independent risk factor for postoperative recurrence
and metastasis in hepatocellular carcinoma (HCC). However, the specific protein expression …