Tocilizumab: a review in rheumatoid arthritis

LJ Scott - Drugs, 2017 - Springer
Intravenous (IV) and subcutaneous (SC) tocilizumab (RoActemra®), an IL-6 receptor
antagonist, are approved (±methotrexate) in numerous countries throughout the world, for …

Early diagnosis and treatment of rheumatoid arthritis

EA Littlejohn, SU Monrad - Primary Care: Clinics in …, 2018 - primarycare.theclinics.com
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that primarily targets
synovial joints, resulting in pain and functional limitations. It is the most common …

Pathogenesis, clinical features, and treatment strategy for rheumatoid arthritis-associated interstitial lung disease

M Akiyama, Y Kaneko - Autoimmunity reviews, 2022 - Elsevier
Rheumatoid arthritis is an autoimmune disease that primarily affects the joints. The
emergence of highly effective anti-rheumatic drugs such as biologic agents and janus …

Treating juvenile idiopathic arthritis to target: recommendations of an international task force

A Ravelli, A Consolaro, G Horneff, RM Laxer… - Annals of the …, 2018 - ard.bmj.com
Recent therapeutic advances in juvenile idiopathic arthritis (JIA) have made remission an
achievable goal for most patients. Reaching this target leads to improved outcomes. The …

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2019 update

JS Smolen, RBM Landewé, JWJ Bijlsma… - Annals of the …, 2020 - ard.bmj.com
Objectives To provide an update of the European League Against Rheumatism (EULAR)
rheumatoid arthritis (RA) management recommendations to account for the most recent …

[HTML][HTML] An expert consensus framework for asthma remission as a treatment goal

A Menzies-Gow, M Bafadhel, WW Busse… - Journal of Allergy and …, 2020 - Elsevier
With novel therapies in development, there is an opportunity to consider asthma remission
as a treatment goal. In this Rostrum, we present a generalized framework for clinical and …

Roles of heat shock proteins in apoptosis, oxidative stress, human inflammatory diseases, and cancer

PC Ikwegbue, P Masamba, BE Oyinloye, AP Kappo - Pharmaceuticals, 2017 - mdpi.com
Heat shock proteins (HSPs) play cytoprotective activities under pathological conditions
through the initiation of protein folding, repair, refolding of misfolded peptides, and possible …

[HTML][HTML] Baricitinib in patients with inadequate response or intolerance to conventional synthetic DMARDs: results from the RA-BUILD study

M Dougados, D van der Heijde, YC Chen… - Annals of the …, 2017 - ard.bmj.com
Background Baricitinib is an oral, reversible, selective Janus kinase 1 and 2 inhibitor.
Methods In this phase III, double-blind 24-week study, 684 biologic disease-modifying …

Current therapeutic options in the treatment of rheumatoid arthritis

BM Köhler, J Günther, D Kaudewitz… - Journal of clinical …, 2019 - mdpi.com
Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic
inflammation of the joints. Untreated RA leads to a destruction of joints through the erosion …

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2022 update

JS Smolen, RBM Landewé, SA Bergstra… - Annals of the …, 2023 - ard.bmj.com
Objectives To provide an update of the EULAR rheumatoid arthritis (RA) management
recommendations addressing the most recent developments in the field. Methods An …