New and emerging approaches to better define sleep disruption and its consequences
Current approaches to quantify and diagnose sleep disorders and circadian rhythm
disruption are imprecise, laborious, and often do not relate well to key clinical and health …
disruption are imprecise, laborious, and often do not relate well to key clinical and health …
[HTML][HTML] Rhythms in barriers and fluids: circadian clock regulation in the aging neurovascular unit
The neurovascular unit is where two very distinct physiological systems meet: The central
nervous system (CNS) and the blood. The permeability of the barriers separating these …
nervous system (CNS) and the blood. The permeability of the barriers separating these …
Evening home lighting adversely impacts the circadian system and sleep
The regular rise and fall of the sun resulted in the development of 24-h rhythms in virtually all
organisms. In an evolutionary heartbeat, humans have taken control of their light …
organisms. In an evolutionary heartbeat, humans have taken control of their light …
The dim light melatonin onset across ages, methodologies, and sex and its relationship with morningness/eveningness
DJ Kennaway - Sleep, 2023 - academic.oup.com
The onset of melatonin secretion, the dim light melatonin onset (DLMO), is a tool for
determining the phase of the circadian timing system. Although small studies have …
determining the phase of the circadian timing system. Although small studies have …
Towards a framework for light-dosimetry studies: Methodological considerations
SL Hartmeyer, FS Webler… - Lighting Research & …, 2023 - journals.sagepub.com
For field research of non-visual effects of light, accurate measurement of personal light
exposure is required. A consensus framework for light-dosimetry could improve non-visual …
exposure is required. A consensus framework for light-dosimetry could improve non-visual …
The seasons within: a theoretical perspective on photoperiodic entrainment and encoding
C Schmal - Journal of Comparative Physiology A, 2024 - Springer
Circadian clocks are internal timing devices that have evolved as an adaption to the
omnipresent natural 24 h rhythmicity of daylight intensity. Properties of the circadian system …
omnipresent natural 24 h rhythmicity of daylight intensity. Properties of the circadian system …
[HTML][HTML] Uncovering personal circadian responses to light through particle swarm optimization
J Vicente-Martínez, MÁ Bonmatí-Carrión… - Computer Methods and …, 2024 - Elsevier
Background and objectives Kronauer's oscillator model of the human central pacemaker is
one of the most commonly used approaches to study the human circadian response to light …
one of the most commonly used approaches to study the human circadian response to light …
Genome-wide gene by environment study of time spent in daylight and chronotype identifies emerging genetic architecture underlying light sensitivity
Abstract Study Objectives Light is the primary stimulus for synchronizing the circadian clock
in humans. There are very large interindividual differences in the sensitivity of the circadian …
in humans. There are very large interindividual differences in the sensitivity of the circadian …
Estimating circadian phase in elementary school children: leveraging advances in physiologically informed models of circadian entrainment and wearable devices
Abstract Study Objectives Examine the ability of a physiologically based mathematical
model of human circadian rhythms to predict circadian phase, as measured by salivary dim …
model of human circadian rhythms to predict circadian phase, as measured by salivary dim …
Impact of light schedules and model parameters on the circadian outcomes of individuals
Key differences exist between individuals in terms of certain circadian-related parameters,
such as intrinsic period and sensitivity to light. These variations can differentially impact …
such as intrinsic period and sensitivity to light. These variations can differentially impact …