Nociplastic pain is the semantic term suggested by the international community of pain
researchers to describe a third category of pain that is mechanistically distinct from …

The term “nociplastic pain” was introduced by the International Association for the Study of
Pain (IASP) in 2017 as a third mechanistic pain descriptor in addition to nociceptive and …

Pain is a multidimensional experience with sensory-discriminative, affective-motivational,
and cognitive-evaluative components. Pain aversiveness is one principal cause of suffering …

Background Over the past few years, researchers have investigated whether varying
menstrual statuses and oestrogen levels could affect the likelihood of temporomandibular …

Importance Chronic pelvic pain (CPP) is a challenging condition that affects an estimated
26% of the world's female population. Chronic pelvic pain accounts for 40% of …

Chronic pain is maintained in part by central sensitization, a phenomenon of synaptic
plasticity, and increased neuronal responsiveness in central pain pathways after painful …

Despite their ubiquitous presence, placebos and placebo effects retain an ambiguous and
unsettling presence in biomedicine. Specifically focused on chronic pain, this review …

Migraine is a complex condition in which genetic predisposition interacts with other
biological and environmental factors determining its course. A hyperresponsive brain cortex …

• Endometriosis is a common disorder that can cause pelvic pain and infertility, may involve
multiple organ systems and can adversely affect quality of life.• The cause of endometriosis …

Background: Opioid use, abuse, and adverse consequences, including death, have
escalated at an alarming rate since the 1990s. In an attempt to control opioid abuse …