Ocular fixation is a dynamic process that is actively controlled by many of the same brain
structures involved in the control of eye movements, including the superior colliculus …

Leber congenital amaurosis (LCA) is a rare hereditary retinal degeneration caused by
mutations in more than a dozen genes. RPE65, one of these mutated genes, is highly …

Head-mounted visualization technology, often in the form of virtual, augmented, and mixed
reality (VAMR), has revolutionized how visual disorders may be approached clinically. In this …

Purpose.: Adeno-associated virus serotype 2 (AAV2) has been shown to be effective in
transducing inner retinal neurons after intravitreal injection in several species. However …

The aim of this study was to explore the plasticity of fixation in patients with central vision
loss. Most of these patients use preferred retinal loci (PRLs) in the healthy eccentric part of …

Microperimeters embody technological abilities required to assess components of residual
visual functions and functional vision. Residual visual functions and functional vision after …

Brain plasticity refers to the ability of synaptic connections to adapt their function and
structure in response to experience, including environmental changes, sensory deprivation …

Background: Eccentric viewing in macular disease has been described for half a century.
However, a clear definition of eccentric viewing and preferred retinal locus (PRL) does not …

In healthy vision, the fovea provides high acuity and serves as the locus for fixation achieved
through saccadic eye movements. Bilateral loss of the foveal regions in both eyes causes …

Purpose Over the last two decades, magnetic resonance imaging (MRI) has been widely
used in neuroscience research to assess both structure and function in the brain in health …