Acrolein induces activation of the epidermal growth factor receptor of human keratinocytes for cell death

K Takeuchi, M Kato, H Suzuki… - Journal of cellular …, 2001 - Wiley Online Library
Acrolein, which is a highly reactive formaldehyde generated by lipid peroxidation, can affect
skin and cause various disorders. The effect of exposure of human keratinocytes to acrolein …

Protective effects of the dietary supplementation of turmeric (Curcuma longa L.) on sodium arsenite-induced biochemical perturbation in mice

MR Karim, A Haque, K Islam, N Ali… - Bangladesh Medical …, 2010 - banglajol.info
The present study was undertaken to evaluate the protective effect of turmeric powder on
arsenic toxicity through mice model. Swiss albino male mice were divided into four groups …

Hu1D10 induces apoptosis concurrent with activation of the AKT survival pathway in human chronic lymphocytic leukemia cells

AP Mone, P Huang, H Pelicano, CM Cheney, JM Green… - Blood, 2004 - ashpublications.org
The 1D10 antigen is the target for Hu1D10 (apolizumab), a humanized HLA-DR β-chain–
specific antibody that is currently in clinical trials for hematologic malignancies. We …

Integrated approach to immunotoxicity: electron transfer, reactive oxygen species, antioxidants, cell signaling, and receptors

P Kovacic, R Somanathan - Journal of Receptors and Signal …, 2008 - Taylor & Francis
As with all body organs, the immune system is subjected to attack by a variety of toxins.
Serious consequences can result because the immune organs serve as a defense against …

Arsenite induces apoptosis in hepatocytes through an enhancement of the activation of Jun N-terminal kinase and p38 mitogen-activated protein kinase caused by …

T Suzuki, I Tsukamoto - Toxicology letters, 2006 - Elsevier
To investigate the effects of arsenite on cell proliferation and the signal transduction in
hapatocytes in vivo, rats received a single injection of sodium arsenite immediately after …

Arsenic trioxide therapy in acute promyelocytic leukemia and beyond: from bench to bedside

MT Rojewski, S Körper, H Schrezenmeier - Leukemia & lymphoma, 2004 - Taylor & Francis
Arsenic trioxide (As2O3) has a long history of use in medicine. However, it was almost
forgotten in Western medicine in the recent centuries. Prompted by reports from China about …

[HTML][HTML] Efficacy of crude extract of Emblica officinalis (amla) in arsenic-induced oxidative damage and apoptosis in splenocytes of mice

MK Singh, SS Yadav, RS Yadav, US Singh… - Toxicology …, 2014 - ncbi.nlm.nih.gov
Objective: In view of increasing risk of arsenic exposure due to occupational and non-
occupational settings, the present study has been focused to investigate the protective …

Sodium arsenite exposure alters cell migration, focal adhesion localization and decreases tyrosine phosphorylation of focal adhesion kinase in H9C2 myoblasts

SL Yancy, EA Shelden, RR Gilmont… - Toxicological …, 2005 - academic.oup.com
Exposure to the environmental toxicant arsenic is reported to produce a variety of effects
including disruption of signal transduction pathways, cell proliferation, and apoptosis. This …

Excessive Cu2+ deteriorates arsenite-induced apoptosis in chicken brain and resulting in immunosuppression, not in homeostasis

Y Wang, H Zhao, X Yang, M Mu, H Zong, L Luo, M Xing - Chemosphere, 2020 - Elsevier
Trace elements such as copper (Cu) and arsenic (As) are two of the major contaminants and
well-known inducers of cognitive deficits and neurobehavioral changes. This study …

Caspase activation is accelerated by the inhibition of arsenite-induced, membrane rafts-dependent Akt activation

K Hossain, AA Akhand, Y Kawamoto, J Du… - Free Radical Biology …, 2003 - Elsevier
Renewed interest in arsenic has been shown recently due to its dual nature of being a
potent toxin and a drug for treatment of acute promyelocytic leukemia (APL) because of its …