Excessive caloric intake in a form of high-fat diet (HFD) was long thought to be the major risk
factor for development of obesity and its complications, such as fatty liver disease and …

Metabolic syndrome (MS) is the term for a combination of hypertension, dyslipidemia, insulin
resistance, and central obesity as factors leading to cardiovascular and metabolic disease …

Primary liver cancer is the third leading cause of cancer-related death worldwide. Most
patients are diagnosed at late stages with poor prognosis; thus, identification of modifiable …

There is growing evidence of 'food addiction'(FA) in sugar-and fat-bingeing animals. The
purpose of this study was to investigate the legitimacy of this disorder in the human …

High dietary fructose is a major contributor to insulin resistance and metabolic syndrome,
disturbing tissue and organ functions. Fructose is mainly absorbed into systemic circulation …

Few medications are available for meeting the increasing disease burden of nonalcoholic
fatty liver disease (NAFLD) and its progressive stage, nonalcoholic steatohepatitis (NASH) …

Type 2 diabetes mellitus (DM) has reached pandemic proportions and effective prevention
strategies are wanted. Its onset is accompanied by cellular distress, the nuclear factor …

As dietary exposure to fructose has increased over the past 40 years, there is growing
concern that high fructose consumption in humans may be in part responsible for the rising …

Aims: Increased fructose consumption predisposes the liver to nonalcoholic fatty liver
disease (NAFLD), but the mechanisms are elusive. Thioredoxin-interacting protein (TXNIP) …

Background Curcumin is a natural polyphenol with beneficial effects on NAFLD patients and
NAFLD is accompanied by metabolism decompensation. Methods This study was focused …