[HTML][HTML] Eleven strategies for making reproducible research and open science training the norm at research institutions

FE Kohrs, S Auer, A Bannach-Brown, S Fiedler… - Elife, 2023 - elifesciences.org
Reproducible research and open science practices have the potential to accelerate scientific
progress by allowing others to reuse research outputs, and by promoting rigorous research …

Guidelines on antibody use in physiology research

HL Brooks, LE de Castro Brás… - American Journal …, 2024 - journals.physiology.org
Antibodies are one of the most used reagents in scientific laboratories and are critical
components for a multitude of experiments in physiology research. Over the past decade …

[HTML][HTML] Glucocorticoids modulate neural activity via a rapid non-genomic effect on Kv2. 2 channels in the central nervous system

Y Wang, Y Zhang, J Hu, C Pan, Y Gao, Q Liu, W Xu… - Neurobiology of …, 2024 - Elsevier
Glucocorticoids are primary stress hormones that exert neuronal effects via both genomic
and non-genomic signaling pathways. However, their rapid non-genomic effects and …

Production of monoclonal antibodies against botulinum neurotoxin in Nicotiana benthamiana

K Sangprasat, CJI Bulaon, K Rattanapisit… - Human Vaccines & …, 2024 - Taylor & Francis
Botulism is a fatal neurologic disease caused by the botulinum toxin (BoNT) produced by
Clostridium botulinum. It is a rare but highly toxic disease with symptoms, such as cramps …

Brain organoids engineered to give rise to glia and neural networks after 90 days in culture exhibit human-specific proteoforms

TJ Wenzel, DD Mousseau - Frontiers in Cellular Neuroscience, 2024 - frontiersin.org
Human brain organoids are emerging as translationally relevant models for the study of
human brain health and disease. However, it remains to be shown whether human-specific …

[HTML][HTML] Specific, sensitive and quantitative protein detection by in-gel fluorescence

ACD Fuchs - Nature Communications, 2023 - nature.com
Recombinant proteins in complex solutions are typically detected with tag-specific
antibodies in Western blots. Here we describe an antibody-free alternative in which tagged …

ARIADNE–a scientific navigator to find your way through the resource labyrinth and a 10 step roadmap for research projects

H Hartmann, CN Gürsoy, A Lischke, M Mueckstein… - 2023 - osf.io
Performing high-quality research is a challenging endeavor, especially for early career
researchers (ECRs). Most research is characterized by an experiential learning approach …

Protein expression profiles in brain organoids are more similar to those in human brain parenchyma than in mouse brain parenchyma

TJ Wenzel, DD Mousseau - bioRxiv, 2023 - biorxiv.org
Human brain organoids are emerging as relevant models for the study of human brain
health and disease. However, it has not been shown whether human brain organoids exhibit …

[HTML][HTML] Changes in protein expression of NMDA glutamate receptor and Pannexin-1 channel in gastric antrum tissue of rats with type 2 diabetes and treated with …

H Rezazadeh Mehrizi, N Soltani… - Feyz Medical …, 2023 - feyz.kaums.ac.ir
Methods: In this experimental study, 18 male Wistar rats weighing approximately 80-90
grams were randomly assigned into 3 groups (6 rats each): 1) control with standard diet, 2) …

Computational Methods to Detect Potential Problems in Publication Content and Journals

H Zhuang - 2023 - search.proquest.com
The development of modern information technology and social media has made accessing
new scientific discoveries relatively easy. Unfortunately, readers can also be exposed to …