The signal pathways and treatment of cytokine storm in COVID-19

L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - Signal transduction and …, 2021 - nature.com
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic has become a global crisis
and is more devastating than any other previous infectious disease. It has affected a …

The SARS-CoV-2 nucleocapsid protein and its role in viral structure, biological functions, and a potential target for drug or vaccine mitigation

Z Bai, Y Cao, W Liu, J Li - Viruses, 2021 - mdpi.com
The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on the world
is still expanding. Thus, there is an urgent need to better understand this novel virus and find …

Impacts of COVID-19 pandemic on urban park visitation: a global analysis

D Geng, J Innes, W Wu, G Wang - Journal of forestry research, 2021 - Springer
The COVID-19 pandemic has resulted in over 33 million confirmed cases and over 1 million
deaths globally, as of 1 October 2020. During the lockdown and restrictions placed on public …

[PDF][PDF] Large-scale multi-omic analysis of COVID-19 severity

KA Overmyer, E Shishkova, IJ Miller, J Balnis… - Cell systems, 2021 - cell.com
We performed RNA-seq and high-resolution mass spectrometry on 128 blood samples from
COVID-19-positive and COVID-19-negative patients with diverse disease severities and …

Gastrointestinal symptoms associated with COVID-19: impact on the gut microbiome

S Villapol - Translational Research, 2020 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the
greatest worldwide pandemic since the 1918 flu. The consequences of the coronavirus …

HIF-1α promotes SARS-CoV-2 infection and aggravates inflammatory responses to COVID-19

M Tian, W Liu, X Li, P Zhao, MA Shereen… - … and Targeted Therapy, 2021 - nature.com
Cytokine storm induced by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-
2) is a major pathological feature of Coronavirus Disease 2019 (COVID-19) and a crucial …

The ORF6, ORF8 and nucleocapsid proteins of SARS-CoV-2 inhibit type I interferon signaling pathway

JY Li, CH Liao, Q Wang, YJ Tan, R Luo, Y Qiu, XY Ge - Virus research, 2020 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel human
coronavirus causing the pandemic of severe pneumonia (Coronavirus Disease 2019 …

[HTML][HTML] Biomarkers in COVID-19: an up-to-date review

M Samprathi, M Jayashree - Frontiers in pediatrics, 2021 - frontiersin.org
The ongoing pandemic of coronavirus disease 2019 (COVID-19) poses several challenges
to clinicians. Timely diagnosis and hospitalization, risk stratification, effective utilization of …

[HTML][HTML] COVID-19: is there evidence for the use of herbal medicines as adjuvant symptomatic therapy?

D Silveira, JM Prieto-Garcia, F Boylan… - Frontiers in …, 2020 - frontiersin.org
Background Current recommendations for the self-management of SARS-Cov-2 disease
(COVID-19) include self-isolation, rest, hydration, and the use of NSAID in case of high fever …

The role and therapeutic potential of NF-kappa-B pathway in severe COVID-19 patients

A Hariharan, AR Hakeem, S Radhakrishnan… - …, 2021 - Springer
Abstract Coronavirus disease 2019 (COVID-19) pandemic has affected health care systems
worldwide. Severe presentations of COVID-19 such as severe pneumonia and acute …