Withanone from Withania somnifera Attenuates SARS-CoV-2 RBD and Host ACE2 Interactions to Rescue Spike Protein Induced Pathologies in Humanized Zebrafish …
Purpose SARS-CoV-2 engages human ACE2 through its spike (S) protein receptor binding
domain (RBD) to enter the host cell. Recent computational studies have reported that …
domain (RBD) to enter the host cell. Recent computational studies have reported that …
Antiviral strategies targeting host factors and mechanisms obliging+ ssRNA viral pathogens
The ongoing COVID-19 pandemic, periodic recurrence of viral infections, and the
emergence of challenging variants has created an urgent need of alternative therapeutic …
emergence of challenging variants has created an urgent need of alternative therapeutic …
The nutrition-COVID-19 interplay: a review
Abstract Purpose of Review Nutritional status is affected by the COVID-19 pandemic, directly
or indirectly. Even with the recent rollout of the coronavirus disease 2019 (COVID-19) …
or indirectly. Even with the recent rollout of the coronavirus disease 2019 (COVID-19) …
Oxidative stress‐related mechanisms in SARS‐CoV‐2 infections
J Wieczfinska, P Kleniewska… - Oxidative medicine and …, 2022 - Wiley Online Library
The COVID‐19 pandemic caused relatively high mortality in patients, especially in those
with concomitant diseases (ie, diabetes, hypertension, and chronic obstructive pulmonary …
with concomitant diseases (ie, diabetes, hypertension, and chronic obstructive pulmonary …
Calming the storm: natural immunosuppressants as adjuvants to target the cytokine storm in COVID-19
AE Peter, BV Sandeep, BG Rao… - Frontiers in …, 2021 - frontiersin.org
The COVID-19 pandemic has caused a global health crisis, with no specific antiviral to treat
the infection and the absence of a suitable vaccine to prevent it. While some individuals …
the infection and the absence of a suitable vaccine to prevent it. While some individuals …
[HTML][HTML] Potential of natural astaxanthin in alleviating the risk of cytokine storm in COVID-19
Host excessive inflammatory immune response to SARS-CoV-2 infection is thought to
underpin the pathogenesis of COVID-19 associated severe pneumonitis and acute lung …
underpin the pathogenesis of COVID-19 associated severe pneumonitis and acute lung …
Unpuzzling COVID-19: tissue-related signaling pathways associated with SARS-CoV-2 infection and transmission
The highly infective coronavirus disease 19 (COVID-19) is caused by a novel strain of
coronaviruses–the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
coronaviruses–the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
Impaired immune response mediated by prostaglandin E2 promotes severe COVID-19 disease
M Ricke-Hoch, E Stelling, L Lasswitz, AP Gunesch… - PloS one, 2021 - journals.plos.org
The SARS-CoV-2 coronavirus has led to a pandemic with millions of people affected. The
present study finds that risk-factors for severe COVID-19 disease courses, ie male sex, older …
present study finds that risk-factors for severe COVID-19 disease courses, ie male sex, older …
Targeting sphingosine-1-phosphate signaling in immune-mediated diseases: beyond multiple sclerosis
T Pérez-Jeldres, M Alvarez-Lobos, J Rivera-Nieves - Drugs, 2021 - Springer
Abstract Sphingosine-1-phosphate (S1P) is a bioactive lipid metabolite that exerts its actions
by engaging 5 G-protein-coupled receptors (S1PR1-S1PR5). S1P receptors are involved in …
by engaging 5 G-protein-coupled receptors (S1PR1-S1PR5). S1P receptors are involved in …
Host-pathogen interaction in COVID-19: Pathogenesis, potential therapeutics and vaccination strategies
The current coronavirus pandemic, COVID-19, is the third outbreak of disease caused by the
coronavirus family, after Severe Acute Respiratory Syndrome and Middle East Respiratory …
coronavirus family, after Severe Acute Respiratory Syndrome and Middle East Respiratory …