Diabetes mellitus (DM) is a global health issue in the twenty-first century, and there are
numerous challenges in preventing and alleviating its chronic complications. The herb …

Arginase is a ubiquitous enzyme in the urea cycle (UC) that hydrolyzes L‐arginine to urea
and L‐ornithine. Two mammalian arginase isoforms, arginase1 (ARG1) and arginase2 …

Introduction Recent published clinical trial safety data showed that 41% of Alzheimer
patients experienced amyloid‐related imaging abnormalities (ARIA), marks of …

Endothelial cells (EC) are active participants in the inflammation process. During the
infection, the change in endothelium properties provides the leukocyte infiltrate formation …

The blood levels of microRNA-122 (miR-122) is associated with the severity of
cardiovascular disorders, and targeting it with efficient and safer miR inhibitors could be a …

Introduction Diabetic patients are often accompanied by complications of diabetic vascular
disease, which could lead to heart failure or stroke. In this work, we explored the role of miR …

Advanced glycation end products (AGEs) contribute significantly to vascular dysfunction
(VD) in diabetes. Decreased nitric oxide (NO) is a hallmark in VD. In endothelial cells, NO is …

In recent years hydrogen sulfide (H 2 S) has demonstrated vasculoprotective effects against
cell death, which suggests its promising therapeutic potential for numerous types of disease …

Abstract Ethnopharmacological relevance Cyclocarya paliurus (Batal.) Iljinskaja.(C.
paliurus) is a distinctive traditional Chinese herb, with remarkable hypoglycemic capacity …

Peritoneal dissemination threatens the survival of patients with gastric cancer (GC). Bufalin
is an extract of traditional Chinese medicine, which has been proved to have anticancer …