Lactose characteristics and the generation of the aerosol
The delivery efficiency of dry-powder products for inhalation is dependent upon the drug
formulation, the inhaler device, and the inhalation technique. Dry powder formulations are …
formulation, the inhaler device, and the inhalation technique. Dry powder formulations are …
A review of inverse gas chromatography and its development as a tool to characterize anisotropic surface properties of pharmaceutical solids
Surface properties can profoundly impact the bulk and interfacial behavior of pharmaceutical
solids, and also their manufacturability, processability in drug product processes, dissolution …
solids, and also their manufacturability, processability in drug product processes, dissolution …
[HTML][HTML] Stability of α-lactose monohydrate: The discovery of dehydration triggered solid-state epimerization
T Alzoubi, GP Martin, DJ Barlow, PG Royall - International Journal of …, 2021 - Elsevier
Lactose is present as an excipient in nearly half of all solid medicines. Despite the
assumption of chemical stability, in aqueous solution, the chiral composition of lactose is …
assumption of chemical stability, in aqueous solution, the chiral composition of lactose is …
Formulation pre-screening of inhalation powders using computational atom–atom systematic search method
V Ramachandran, D Murnane… - Molecular …, 2015 - ACS Publications
The synthonic modeling approach provides a molecule-centered understanding of the
surface properties of crystals. It has been applied extensively to understand crystallization …
surface properties of crystals. It has been applied extensively to understand crystallization …
Evaluation of milling method on the surface energetics of molecular crystals using inverse gas chromatography
PE Luner, Y Zhang, YA Abramov… - Crystal growth & …, 2012 - ACS Publications
The objective of this study was to determine whether high shear wet milling (HSWM) has an
impact on the surface properties of model pharmaceutical compounds compared to dry …
impact on the surface properties of model pharmaceutical compounds compared to dry …
[PDF][PDF] Issue title: Lactose as a carrier for inhalation products
The delivery efficiency of dry-powder products for inhalation is dependent upon the drug
formulation, the inhaler device, and the inhalation technique. Dry powder formulations are …
formulation, the inhaler device, and the inhalation technique. Dry powder formulations are …
[引用][C] Solid form diversity of commonly used tableting excipients and its impact–References
PE Luner - 2013