[HTML][HTML] A broad m6A modification landscape in inflammatory bowel disease

K Nie, J Yi, Y Yang, M Deng, Y Yang… - Frontiers in cell and …, 2022 - frontiersin.org
Background and Aims: N6-Methyladenosine (m6A) is the most common post-transcriptional
modification on eukaryotic mRNA, affecting the mRNA's fate. The role of m6A regulation in …

m6A-TSHub: Unveiling the Context-Specific m6A Methylation and m6A-Affecting Mutations in 23 Human Tissues

B Song, D Huang, Y Zhang, Z Wei, J Su… - Genomics …, 2023 - academic.oup.com
As the most pervasive epigenetic marker present on mRNAs and long non-coding RNAs
(lncRNAs), N 6-methyladenosine (m6A) RNA methylation has been shown to participate in …

[HTML][HTML] A New Understanding of Long Non-Coding RNA in Hepatocellular Carcinoma—From m6A Modification to Blood Biomarkers

JW Eun, JY Cheong, JY Jeong, HS Kim - Cells, 2023 - mdpi.com
With recent advancements in biological research, long non-coding RNAs (lncRNAs) with
lengths exceeding 200 nucleotides have emerged as pivotal regulators of gene expression …

N6-Methyladenosine Modification of CDH1 mRNA Promotes PM2.5-Induced Pulmonary Fibrosis via Mediating Epithelial Mesenchymal Transition

J Ning, H Du, Y Zhang, Q Liu, T Jiang… - Toxicological …, 2022 - academic.oup.com
The association between ambient airborne fine particulate matter (PM2. 5) exposure and
respiratory diseases has been investigated in epidemiological studies. To explore the …

[HTML][HTML] m6A-modified circRNAs: detections, mechanisms, and prospects in cancers

S Qin, Q Zhang, Y Xu, S Ma, T Wang, Y Huang, S Ju - Molecular Medicine, 2022 - Springer
Circular RNAs (circRNAs) have become a research hotspot in recent years with their
universality, diversity, stability, conservativeness, and spatiotemporal specificity. N6 …

ZC3H13-mediated N6-methyladenosine modification of PHF10 is impaired by fisetin which inhibits the DNA damage response in pancreatic cancer

C Huang, S Zhou, C Zhang, Y Jin, G Xu, L Zhou… - Cancer letters, 2022 - Elsevier
DNA damage repair is a major barrier for chemotherapy efficacy of pancreatic ductal
adenocarcinoma (PDAC), including the efficacy of platinum-based and gemcitabine/nab …

[HTML][HTML] RBM3 suppresses stemness remodeling of prostate cancer in bone microenvironment by modulating N6-methyladenosine on CTNNB1 mRNA

S Zhang, C Lv, Y Niu, C Li, X Li, Y Shang… - Cell Death & …, 2023 - nature.com
Bone metastasis is the most happened metastatic event in prostate cancer (PCa) and needs
a large effort in treatment. When PCa metastasizes to the bone, the new microenvironment …

Exploring N6-methyladenosine (m6A) modification in tree species: opportunities and challenges

M Ramakrishnan, KS Rajan, S Mullasseri… - Horticulture …, 2024 - academic.oup.com
Abstract N 6-methyladenosine (m6A) in eukaryotes is the most common and widespread
internal modification in mRNA. The modification regulates mRNA stability, translation …

[HTML][HTML] A positive feedback circuit between RN7SK snRNA and m6A readers is essential for tumorigenesis

X Xu, L Ma, X Zhang, S Guo, W Guo, Y Wang, S Qiu… - Molecular Therapy, 2023 - cell.com
N 6-Methyladenosine (m 6 A) RNA modification, methylation at the N6 position of
adenosine, plays critical roles in tumorigenesis. m 6 A readers recognize m 6 A …

UTRdb 2.0: a comprehensive, expert curated catalog of eukaryotic mRNAs untranslated regions

C Lo Giudice, F Zambelli, M Chiara… - Nucleic Acids …, 2023 - academic.oup.com
Abstract The 5′ and 3′ untranslated regions of eukaryotic mRNAs (UTRs) play crucial
roles in the post-transcriptional regulation of gene expression through the modulation of …