J Zhao, X Lin, J Zhuang, F He - Frontiers in Genetics, 2021 - frontiersin.org
Background: Lung adenocarcinoma (LUAD) is the major subtype of lung cancer and is associated with very high mortality. Emerging studies have shown that N6-methyladenosine …
T Li, Z Chen, Z Wang, J Lu, D Chen - Frontiers in Immunology, 2023 - frontiersin.org
Background Identifying predictive markers for breast cancer (BC) prognosis and immunotherapeutic responses remains challenging. Recent findings indicate that N7 …
Epigenetics is the study of heritable changes in gene expression or function without altering the DNA sequence. Important factors are part of epigenetic events, such as methylation …
Z Luo, L Lou, W Qiu, Z Xu, X Xiao - International Journal of Molecular …, 2022 - mdpi.com
N6-methyladenosine (m6A) is the most abundant within eukaryotic messenger RNA modification, which plays an essential regulatory role in the control of cellular functions and …
H Wang, S Wang, Y Zhang, S Bi, X Zhu - Methods, 2022 - Elsevier
Thanks to the tremendous advancement of deep sequencing and large-scale profiling, epitranscriptomics has become a rapidly growing field. As one of the most important parts of …
Abstract N6-methyladenosine (m6A) is one of the most common and well-known internal RNA modifications that occur on mRNAs or ncRNAs. It affects various aspects of RNA …
L Zhao, Y Liu, B Ma, X Liu, R Wei, H Nian - The FASEB Journal, 2023 - Wiley Online Library
Abstract Methyltransferase like 3 (METTL3), a primary N6‐methyladenosine (m6A) methyltransferase, has been implicated in various biological and pathological processes …
Q Liu - Frontiers in genetics, 2022 - frontiersin.org
N6-methyladenosine (m6A) is a dynamic, reversible post-transcriptional modification, and the most common internal modification of eukaryotic messenger RNA (mRNA) …
Post-transcriptional modifications of RNA bases are widespread across all the tree of life and have been linked to RNA maturation, stability, and molecular interactions. RNA …