It is now commonly accepted that most of the mammalian genome is transcribed as RNA, yet
less than 2% of such RNA encode for proteins. A majority of transcribed RNA exists as non …

It has been evident that N6-methyladenosine (m6A)-modified long noncoding RNAs (m6A-
lncRNAs) involves regulating tumorigenesis, invasion, and metastasis for various cancer …

The sensitivity of malignant tissues to T cell-based immunotherapies depends on the
presence of targetable human leukocyte antigen (HLA) class I ligands. Peptide-intrinsic …

Post-transcriptionally RNA modifications, also known as the epitranscriptome, play crucial
roles in the regulation of gene expression during development. Recently, deep learning (DL) …

Background N6-methyladenosine (m6A) is most common internal RNA modification in
eukaryotic cells. Existing evidence shows that m6A is closely related to pathogenesis and …

Background Lung adenocarcinoma (LUAD) patients have a dismal survival rate because of
cancer metastasis and drug resistance. The study aims to identify the genes that …

Background Single nucleotide polymorphisms that affect RNA modification (RNAm-SNPs)
may have functional roles in coronary artery disease (CAD). The aim of this study was to …

RNA modifications affect fundamental biological processes and diseases and are a
research hotspot. Several micro-RNAs (miRNAs) exhibit genetic variant-targeted RNA …

RNA modifications occur through the whole process of gene expression regulation,
including transcription, translation, and post-translational processes. They are closely …

Adipose tissue plays a crucial role in maintaining energy balance, regulating hormones, and
promoting metabolic health. To address disorders related to obesity and develop effective …