The development of siRNA technology has provided new opportunities for gene-specific
inhibition and knockdown, as well as new ideas for the treatment of disease. Four siRNA …

The respiratory tract has been used to deliver biologically active chemicals into the human
body for centuries. However, the lungs are complex in their anatomy and physiology, which …

Antibacterial peptide is a small molecular weight, a substance existing in the biological
body, plays a very important role in congenital immune systems. Today, in various …

Явление Рнкrинтерференции было открыто в 90rе годы XX в. в исследованиях на
нематоде Caenorhabditis elegans. Терминологически, изначально Рнкrинтерференция …

Local pulmonary administration of therapeutic siRNA represents a promising approach to
the treatment of lung fibrosis, which is currently hampered by inefficient delivery. Pancreatic …

With the use of contemporary tools and techniques, it has become possible to more
precisely tune the biochemical mechanisms associated with using nonviral vectors for gene …

RNA 干扰(RNAi) 是一种转录后的基因沉默机制, 从发现至今已逐渐成为疾病治疗的新手段.
小干扰RNA (siRNA) 是RNAi 过程中的效应分子, 已作为药物处于临床研究的不同阶段 …

This chapter discusses the history, current status, and future direction of inhalation delivery
of macromolecule biopharmaceuticals. The advantages and challenges of inhalation …

Central nervous system (CNS) disorders, including neurodegeneration and chronic pain,
and many respiratory diseases would greatly benefit from the specific and potent peptide …

Cardiovascular diseases (CVDs) are extremely predominant worldwide with high morbidity
and mortality. Despite of the advancement in the pharmacological interventions cardiac …