The laboratory rat has been used for a long time as the model of choice in several
biomedical disciplines. Numerous inbred strains have been isolated, displaying a wide …

Abstract Although Autism Spectrum Disorder (ASD) is increasing in diagnostic prevalence,
treatment options are inadequate largely due to limited understanding of ASD's underlying …

Autism spectrum disorder (ASD) is strongly associated with de novo gene mutations. One of
the most commonly affected genes is SCN2A. ASD-associated SCN2A mutations impair the …

Fragile X Syndrome (FXS) is a leading inherited cause of autism and intellectual disability,
resulting from a mutation in the FMR1 gene and subsequent loss of its protein product …

The frontal cortex, especially the anterior cingulate cortex area (ACA), is essential for
exerting cognitive control after errors, but the mechanisms that enable modulation of …

Autism spectrum disorder (ASD) has a multifactorial etiology. Major efforts are underway to
understand the neurobiological bases of ASD and to develop efficacious treatment …

Abstract Rationale Fragile X syndrome (FXS) is the most common form of inherited
intellectual disability (ID) and the leading monogenic cause of autism spectrum disorder …

Background and objective: Autism spectrum disorder (ASD) is a complex
neurodevelopmental disorder for which no treatments exist. Fragile X syndrome (FXS) is the …

Abstract Autism Spectrum Disorder (ASD) is a pervasive neurodevelopmental disorder
emerging in early life characterized by impairments in social interaction, poor verbal and …

Fragile X syndrome (FXS) is the most common cause of inherited intellectual disabilities and
the most prevalent monogenic cause of autism. Although the knockout (KO) of the Fmr1 …