Monoclonal antibody therapies against SARS-CoV-2

D Focosi, S McConnell, A Casadevall… - The Lancet Infectious …, 2022 - thelancet.com
Monoclonal antibodies (mAbs) targeting the spike protein of SARS-CoV-2 have been widely
used in the ongoing COVID-19 pandemic. In this paper, we review the properties of mAbs …

Analysis of SARS-CoV-2 mutations associated with resistance to therapeutic monoclonal antibodies that emerge after treatment.

D Focosi, S McConnell, DJ Sullivan… - Drug Resistance Updates, 2023 - Elsevier
The mutation rate of the Omicron sublineage has led to baseline resistance against all
previously authorized anti-Spike monoclonal antibodies (mAbs). Nevertheless, in case more …

An early warning system for emerging SARS-CoV-2 variants

L Subissi, A von Gottberg, L Thukral, N Worp… - Nature medicine, 2022 - nature.com
An early warning system for emerging SARS-CoV-2 variants | Nature Medicine Skip to main
content Thank you for visiting nature.com. You are using a browser version with limited support …

Maternal immune response and placental antibody transfer after COVID-19 vaccination across trimester and platforms

CG Atyeo, LL Shook, S Brigida, RM De Guzman… - Nature …, 2022 - nature.com
The availability of three COVID-19 vaccines in the United States provides an unprecedented
opportunity to examine how vaccine platforms and timing of vaccination in pregnancy impact …

[HTML][HTML] Inflammatory responses in the placenta upon SARS-CoV-2 infection late in pregnancy

LB Argueta, LA Lacko, Y Bram, T Tada, L Carrau… - Iscience, 2022 - cell.com
The effect of SARS-CoV-2 infection on placental function is not well understood. Analysis of
placentas from women who tested positive at delivery showed SARS-CoV-2 genomic and …

SARS-COV-2 antibody responses to AZD1222 vaccination in West Africa

A Abdullahi, D Oladele, M Owusu, SA Kemp… - Nature …, 2022 - nature.com
Real-world data on vaccine-elicited neutralising antibody responses for two-dose AZD1222
in African populations are limited. We assessed baseline SARS-CoV-2 seroprevalence and …

Comparison of vaccine-induced antibody neutralization against SARS-CoV-2 variants of concern following primary and booster doses of COVID-19 vaccines

AK Hvidt, EAM Baerends, OS Søgaard… - Frontiers in …, 2022 - frontiersin.org
The SARS-CoV-2 pandemic has, as of July 2022, infected more than 550 million people and
caused over 6 million deaths across the world. COVID-19 vaccines were quickly developed …

Predictors of long-term neutralizing antibody titers following COVID-19 vaccination by three vaccine types: the BOOST study

AA Prather, EG Dutcher, J Robinson, J Lin… - Scientific reports, 2023 - nature.com
As concerns related to the COVID-19 pandemic continue, it is critical to understand the
impact of vaccination type on neutralizing antibody response durability as well as to identify …

Molecular evolution of SARS-CoV-2 during the COVID-19 pandemic

LD González-Vázquez, M Arenas - Genes, 2023 - mdpi.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) produced diverse
molecular variants during its recent expansion in humans that caused different …

Humoral response to BNT162b2 vaccine against SARS-CoV-2 variants decays after six months

TJ Lopera, M Chvatal-Medina… - Frontiers in …, 2022 - frontiersin.org
SARS-CoV-2 vaccines have shown very high effectiveness in real-world scenarios.
However, there is compelling evidence for a fast-paced waning of immunity. The increasing …