During the past decade, research on primary liver cancers has particularly highlighted the
uncommon plasticity of differentiated parenchymal liver cells (that is, hepatocytes and …

Background Histological grading typically reflects the biological behavior of solid tumors,
thus providing valuable prognostic information. This is also expected in hepatocellular …

Hepatocellular carcinomas are malignant epithelial neoplasms that originate in the liver and
show exclusively or primarily hepatic differentiation. However, hepatocellular carcinomas …

Hepatocellular carcinoma (HCC) is one of the most common and fatal cancer in the world.
HCC frequently presents with advanced disease, has a high recurrence rate and limited …

Fibrolamellar carcinomas are a unique type of primary liver cancer. They occur most
commonly in children and young adults. Their etiology remains a mystery, as they are not …

Fibrolamellar carcinomas are a unique type of liver carcinoma that arise in non-cirrhotic
livers of young individuals. Despite their distinctive appearance, recent studies have …

Although radiological diagnostics have been progressing, pathological diagnosis remains
the most reliable method for diagnosing liver tumors. In some cases, definite pathological …

Combined hepatocellular‐cholangiocarcinoma is a rare primary neoplasm in the liver. It has
gained increasing recognition recently, which in part may be due to more extensive …

Fibrolamellar carcinoma is a rare malignant primary liver neoplasm with characteristic
histological features that typically arises in young patients without viral hepatitis or cirrhosis …

Fibrolamellar carcinoma (FLC) is a rare, often lethal, liver cancer affecting adolescents and
young adults, for which there are no approved therapeutics. The development of …