Non-coding RNA: role in gestational diabetes pathophysiology and complications

T Filardi, G Catanzaro, S Mardente, A Zicari… - International Journal of …, 2020 - mdpi.com
Gestational Diabetes Mellitus (GDM) is defined as glucose intolerance that develops in the
second or third trimester of pregnancy. GDM can lead to short-term and long-term …

Circular RNA involvement in aging: an emerging player with great potential

H Cai, Y Li, JD Niringiyumukiza, P Su… - Mechanisms of ageing and …, 2019 - Elsevier
Circular RNA (circRNA) is a class of newly discovered noncoding RNA (ncRNA), presenting
as a special covalent loop without a 5′ cap or 3′ tail. Multiple biological properties of …

[HTML][HTML] A novel circular RNA hsa_circ_0020123 exerts oncogenic properties through suppression of miR-144 in non-small cell lung cancer

D Qu, B Yan, R Xin, T Ma - American journal of cancer research, 2018 - ncbi.nlm.nih.gov
Non-small cell lung cancer (NSCLC) is one of the leading causes of cancer-related death
worldwide, while circulatory. Circular RNAs (circRNAs) are found to play important roles in …

Circular RNA circPIP5K1A promotes non‐small cell lung cancer proliferation and metastasis through miR‐600/HIF‐1α regulation

Y Chi, Q Luo, Y Song, F Yang, Y Wang… - Journal of Cellular …, 2019 - Wiley Online Library
Circular RNAs (circRNAs) have an important function in human diseases, especially in
cancer. circRNA hsa_circ_0014130 (circPIP5K1A), a particularly abundant circRNA …

circRNAs signature as potential diagnostic and prognostic biomarker for diabetes mellitus and related cardiovascular complications

M Zaiou - Cells, 2020 - mdpi.com
Circular RNAs (circRNAs) belong to the ever-growing class of naturally occurring noncoding
RNAs (ncRNAs) molecules. Unlike linear RNA, circRNAs are covalently closed transcripts …

circMAP3K4 regulates insulin resistance in trophoblast cells during gestational diabetes mellitus by modulating the miR-6795-5p/PTPN1 axis

R Du, N Wu, Y Bai, L Tang, L Li - Journal of Translational Medicine, 2022 - Springer
Background Insulin resistance (IR) during gestational diabetes mellitus (GDM) has been
linked to dysregulated insulin-PI3K/Akt pathway. A defective insulin-PI3K/Akt pathway and …

Downregulation of hsa_circ_0068087 ameliorates TLR4/NF-κB/NLRP3 inflammasome-mediated inflammation and endothelial cell dysfunction in high glucose …

J Cheng, Q Liu, N Hu, F Zheng, X Zhang, Y Ni, J Liu - Gene, 2019 - Elsevier
Diabetes mellitus (DM) is a chronic, multifactorial metabolic disease whereby insulin
deficiency or resistance results in hyperglycemia. A sustained high glucose environment …

High glucose-induced circHIPK3 downregulation mediates endothelial cell injury

Y Cao, G Yuan, Y Zhang, R Lu - Biochemical and Biophysical Research …, 2018 - Elsevier
High glucose (HG) induces vascular endothelial cell injury. However, the underlying
mechanisms are poorly understood. Circular RNA HIPK3 (circHIPK3) is a highly conserved …

Expression profile of circular RNAs in placentas of women with gestational diabetes mellitus

H Wang, G She, W Zhou, K Liu, J Miao, B Yu - Endocrine journal, 2019 - jstage.jst.go.jp
Forty-five pregnant women who underwent cesarean section, including 30 cases of
gestational diabetes mellitus (GDM) and 15 normal pregnant women, were enrolled in this …

Role of circular RNAs in preeclampsia

N Jia, J Li - Disease markers, 2019 - Wiley Online Library
Circular RNAs (circRNAs) are noncoding RNAs characterized by circular covalently closed
structures, which are generated by back‐splicing. circRNA is more stable and conserved …