Simple Summary Multiple myeloma is a plasma cell disorder that accounts for around 10%
of all haematological malignancies. This neoplasia is often associated with a significant …

Leukemia and lymphoma—the most common hematological malignant diseases—are often
accompanied by complications such as drug resistance, refractory diseases and relapse …

Advanced glycation end products (AGEs) contribute significantly to vascular dysfunction
(VD) in diabetes. Decreased nitric oxide (NO) is a hallmark in VD. In endothelial cells, NO is …

Reduced bioavailability of nitric oxide (NO) is accompanied by endothelial dysfunction,
which precedes clinical signs of atherosclerosis. The metalloenzyme arginase reciprocally …

Red blood cells (RBCs) from patients with type 2 diabetes mellitus (T2DM) induce
endothelial dysfunction and impair cardiac function following ischemia via increase in RBC …

The mechanisms underlying endothelial dysfunction in Type 1 and Type 2 diabetes (T1DM
and T2DM) are unresolved. The red blood cells (RBCs) with increased arginase activity …

Background There is great interest to understand causal pathophysiological correlation
between obesity and diabetes mellitus (DM). Vascular endothelial dysfunction is crucially …

The occurrence and development of diabetic vascular diseases are closely linked to
inflammation‐induced endothelial dysfunction. Puerarin (Pue), the primary component of …

Purinergic signaling may be altered in diabetes accounting for endothelial dysfunction.
Uridine adenosine tetraphosphate (Up4A), a novel dinucleotide substance, regulates …

Postprandial hyperglycemia interferes with vascular reactivity and is a strong predictor of
cardiovascular disease. Macronutrient preloads reduce postprandial hyperglycemia in …