Neutralizing antibodies are known to have a crucial role in protecting against SARS-CoV-2
infection and have been suggested to be a useful correlate of protection for vaccine clinical …

In the broad range of human diseases, thrombo-inflammation appears as a clinical
manifestation. Clinically, it is well characterized in context of superficial thrombophlebitis that …

Increasing evidence suggests that activation of the complement system plays a key role in
the pathogenesis and disease severity of Coronavirus disease 2019 (COVID-19). We used a …

COVID-19 is characterised by a broad spectrum of clinical and pathological features. Natural
killer (NK) cells play an important role in innate immune responses to viral infections. Here …

Sepsis is accompanied by thrombocytopenia and the severity of the thrombocytopenia is
associated with mortality. This thrombocytopenia is characteristic of disseminated …

Viral infections are often associated with platelet activation and haemostatic complications.
In line, low platelet counts represent a hallmark for poor prognosis in many infectious …

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus was identified in
China in 2019 as the causative agent of COVID-19, and quickly spread throughout the …

Background Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare
complication of adenoviral vector–based vaccines against SARS-CoV-2. This syndrome is …

Spleen tyrosine kinase (SYK) is a previously unidentified therapeutic target that inhibits
neutrophil and macrophage activation in coronavirus disease 2019 (COVID-19) …

Cerebral venous (sinus) thrombosis (CVT) is an unusual manifestation of venous thrombosis
causing severe neurological impairment and seizures,. Molecular mechanisms underlying …