Tumor immune microenvironment (TIME), a tumor-derived immune component, is proven to
be closely related to the development, metastasis, and recurrence of tumors. Gut microbiota …

Background The gut microbiome is closely related to gastrointestinal (GI) cancer, but the
causality of gut microbiome with GI cancer has yet to be fully established. We conducted this …

Patients with metastatic esophageal squamous cell carcinoma (ESCC) have a grave
prognosis with limited life expectancy. Here, a phase II clinical trial was conducted to …

Digestive cancers are among the leading causes of cancer death in the world. However, the
mechanisms of cancer development and progression are not fully understood. Accumulating …

Background: The causative implications remain ambiguous. Consequently, this study aims
to evaluate the putative causal relationship between gut microbiota and Esophageal cancer …

Background Evidence from numerous observational studies and clinical trials has linked gut
microbiota and metabolites to digestive tract cancer. However, the causal effect between …

Tobacco use is known to cause health damage, partly by changing the mouth, respiratory
tract, and gut-related microbiomes. This study aims to identify the associations between the …

T2D and its complications are significant threats to human health and are among the most
concerning metabolic diseases worldwide. Previous studies have revealed that Glycyrrhiza …

Purpose The gut microbiome plays an important role in cancer pathogenesis and therapy.
Some studies have reported that specific bacteria in tumor tissues may contribute to the …

Background Increasing evidence suggests that esophageal cancer (ESCA) may be
correlated with gut flora. However, their causal connection remains unclear. This study …