[HTML][HTML] E3 ubiquitin ligase-dependent regulatory mechanism of TRIM family in carcinogenesis
G Zhang, Y Zhang, L Chen, L Liu, X Gao - Cancer Insight, 2023 - anserpress.org
Tripartite motif-containing (TRIM) proteins consist of over 80 proteins, the majority of which
exhibit E3 ubiquitin ligase activity. E3 ligases have a critical role in various cellular …
exhibit E3 ubiquitin ligase activity. E3 ligases have a critical role in various cellular …
Association of the TRIM family protein with survival outcomes and clinicopathological features in colorectal cancer: a systematic review and meta-analysis
Y Wu, C Chen, X Hua, C Zhao, H Min - BMC cancer, 2024 - Springer
Background The tripartite motif (TRIM) proteins have been reported to play crucial roles in
various malignancies. However, the clinical significance of TRIM proteins in colorectal …
various malignancies. However, the clinical significance of TRIM proteins in colorectal …
Ubiquitin ligase TRIM15 promotes the progression of pancreatic cancer via the upregulation of the IGF2BP2-TLR4 axis
H Cai, J Zhao, Q Zhang, H Wu, Y Sun, F Guo… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Background The tripartite motif family, predominantly characterized by its E3 ubiquitin ligase
activities, is involved in various cellular processes including signal transduction, apoptosis …
activities, is involved in various cellular processes including signal transduction, apoptosis …
Blood transfusion might not be recommended for gastric cancer patients with pretransfusion minimum hemoglobin values higher than 90 g/L: a real-world study …
W Wang, C Sun, L Zhao, X Han, X Luan… - … Journal of Surgery, 2024 - journals.lww.com
Background: There was no consistent evidence whether perioperative blood transfusion
(PBT) affects the long-term survival of gastric cancer (GC) patients after undergoing …
(PBT) affects the long-term survival of gastric cancer (GC) patients after undergoing …
TRIM14 suppressed the progression of NSCLC via hexosamine biosynthesis pathway
S Wei, M Ai, Y Zhan, J Yu, T Xie, Q Hu, Y Fang… - …, 2024 - academic.oup.com
Abstract Tripartite Motif 14 (TRIM14) is an oncoprotein that belongs to the E3 ligase TRIM
family, which is involved in the progression of various tumors except for non-small cell lung …
family, which is involved in the progression of various tumors except for non-small cell lung …
[HTML][HTML] Modulator of TMB-associated immune infiltration (MOTIF) predicts immunotherapy response and guides combination therapy
Patients with high tumor mutational burden (TMB) levels do not consistently respond to
immune checkpoint inhibitors (ICIs), possibly because a high TMB level does not …
immune checkpoint inhibitors (ICIs), possibly because a high TMB level does not …
CCT6A promotes cell proliferation in colon cancer by targeting BIRC5 associated with p53 status
H Zhang, T Zheng, C Qin, X Zhang, H Lin… - Cancer Gene …, 2024 - nature.com
Abstract Chaperonin-containing TCP1 (CCT) is a multi-subunit complex, known to
participate the correct folding of many proteins. Currently, the mechanism underlying CCT …
participate the correct folding of many proteins. Currently, the mechanism underlying CCT …
[PDF][PDF] Predictive Biomarkers in PD-1/PD-L1 Immunotherapy Response: A Machine Learning Approach Using Gene Sequencing Data.
Cancer, a leading cause of premature death globally, has seen a surge in new cases,
projected to reach 28.4 million by 2040. Immunotherapy with immune checkpoint inhibitors …
projected to reach 28.4 million by 2040. Immunotherapy with immune checkpoint inhibitors …