Keep out! SARS-CoV-2 entry inhibitors: their role and utility as COVID-19 therapeutics

L Chitsike, P Duerksen-Hughes - Virology Journal, 2021 - Springer
The COVID-19 pandemic has put healthcare infrastructures and our social and economic
lives under unprecedented strain. Effective solutions are needed to end the pandemic while …

Nano-antivirals: A comprehensive review

FS Hussain, NQ Abro, N Ahmed, SQ Memon… - Frontiers in …, 2022 - frontiersin.org
Nanoparticles can be used as inhibitory agents against various microorganisms, including
bacteria, algae, archaea, fungi, and a huge class of viruses. The mechanism of action …

Lessons learned: new insights on the role of cytokines in COVID-19

M Buszko, A Nita-Lazar, JH Park, PL Schwartzberg… - Nature …, 2021 - nature.com
In the midst of resurging COVID-19 cases, the second NIH/FDA virtual COVID-19 and
Cytokines symposium was held on 1 December 2020, focusing on longitudinal studies of …

Efficacy of telemedicine and telemonitoring in at-home monitoring of patients with COVID-19

E Casariego-Vales, R Blanco-Lopez… - Journal of clinical …, 2021 - mdpi.com
Aim: this work aims to assess if telemedicine and telemonitoring are clinically useful and
safe for at-home monitoring of Coronavirus disease 2019 (COVID-19) patients. Methods …

The use of tocilizumab in patients with COVID-19: a systematic review, meta-analysis and trial sequential analysis of randomized controlled studies

AE Maraolo, A Crispo, M Piezzo, P Di Gennaro… - Journal of clinical …, 2021 - mdpi.com
Background: Among the several therapeutic options assessed for the treatment of
coronavirus disease 2019 (COVID-19), tocilizumab (TCZ), an antagonist of the interleukine …

Use of antivirals in SARS-CoV-2 infection. Critical review of the role of remdesivir

S Moreno, B Alcázar, C Dueñas… - Drug Design …, 2022 - Taylor & Francis
The aim of this report is to review the literature and shed light on the uncertainties
surrounding the use of antiviral agents in general and remdesivir in COVID-19 patients. This …

Progress and pitfalls of a year of drug repurposing screens against COVID-19

J Sourimant, M Aggarwal, RK Plemper - Current Opinion in Virology, 2021 - Elsevier
Near the end of 2019, a new betacoronavirus started to efficiently transmit between humans,
resulting in the current COVID-19 pandemic. Unprecedented worldwide efforts were made to …

Peptide binder with high-affinity for the SARS-CoV-2 spike receptor-binding domain

L Yu, R Wang, T Wen, L Liu, T Wang, S Liu… - … Applied Materials & …, 2022 - ACS Publications
Rapid antigen detection tests are urgently needed for the early diagnosis of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). The discovery of a binder with high …

[HTML][HTML] Early alveolar epithelial cell necrosis is a potential driver of COVID-19-induced acute respiratory distress syndrome

K Tojo, N Yamamoto, N Tamada, T Mihara, M Abe… - Iscience, 2023 - cell.com
Acute respiratory distress syndrome (ARDS) with COVID-19 is aggravated by
hyperinflammatory responses even after the peak of the viral load has passed; however, its …

[HTML][HTML] Aspectos básicos de la COVID-19 para el manejo desde atención primaria

JM Molero-García, J Arranz-Izquierdo… - Atención primaria, 2021 - Elsevier
El SARS-CoV-2 se transmite de persona a persona por inhalación o por el contacto con
gotas y aerosoles respiratorios. El período de incubación mediano es 5, 1 días. Fiebre, tos …