Covid-19 and COPD

JM Leung, M Niikura, CWT Yang… - European Respiratory …, 2020 - Eur Respiratory Soc
As of 11 July, 2020, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the
virus responsible for the coronavirus disease 2019 (COVID-19) pandemic has infected over …

The immune system and COVID-19: Friend or foe?

F Yazdanpanah, MR Hamblin, N Rezaei - Life sciences, 2020 - Elsevier
Abstract Aim Coronavirus disease 2019 (COVID-19) is a novel highly contagious infection
caused by SARS-CoV-2, which has been became a global public health challenge. The …

[HTML][HTML] SARS-CoV-2 infection depends on cellular heparan sulfate and ACE2

TM Clausen, DR Sandoval, CB Spliid, J Pihl… - Cell, 2020 - cell.com
We show that SARS-CoV-2 spike protein interacts with both cellular heparan sulfate and
angiotensin-converting enzyme 2 (ACE2) through its receptor-binding domain (RBD) …

SARS-CoV-2–triggered neutrophil extracellular traps mediate COVID-19 pathology

FP Veras, MC Pontelli, CM Silva… - Journal of Experimental …, 2020 - rupress.org
Severe COVID-19 patients develop acute respiratory distress syndrome that may progress to
cytokine storm syndrome, organ dysfunction, and death. Considering that neutrophil …

Low testosterone levels predict clinical adverse outcomes in SARS‐CoV‐2 pneumonia patients

G Rastrelli, V Di Stasi, F Inglese, M Beccaria… - …, 2021 - Wiley Online Library
Background The pandemic of new severe acute respiratory syndrome (SARS) due to
coronavirus (CoV) 2 (SARS‐CoV‐2) has stressed the importance of effective diagnostic and …

[HTML][HTML] A network medicine approach to investigation and population-based validation of disease manifestations and drug repurposing for COVID-19

Y Zhou, Y Hou, J Shen, R Mehra, A Kallianpur… - PLoS …, 2020 - journals.plos.org
The global coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to unprecedented social and …

Asthma and COVID-19: an update

Y Adir, W Saliba, A Beurnier… - European Respiratory …, 2021 - Eur Respiratory Soc
As the world faces the coronavirus disease 2019 (COVID-19) pandemic due to severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, concerns have been raised …

[HTML][HTML] Smoking increases the risk of infectious diseases: A narrative review

C Jiang, Q Chen, M Xie - Tobacco Induced Diseases, 2020 - ncbi.nlm.nih.gov
Smoking is relevant to infectious diseases resulting in increased prevalence and mortality. In
this article, we aim to provide an overview of the effects of smoking in various infections and …

Drugs targeting various stages of the SARS-CoV-2 life cycle: Exploring promising drugs for the treatment of Covid-19

R Poduri, G Joshi, G Jagadeesh - Cellular signalling, 2020 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a positive-sense,
single-stranded RNA virus that causes the potentially lethal Covid-19 respiratory tract …

Roles of extracellular vesicles in the aging microenvironment and age‐related diseases

Y Yin, H Chen, Y Wang, L Zhang… - Journal of extracellular …, 2021 - Wiley Online Library
Cellular senescence is a persistently hypoproliferative state with diverse stressors in a
specific aging microenvironment. Senescent cells have a double‐edged sword effect: they …