Triple negative breast cancer (TNBC) tends to form aggressive tumors associated with high
mortality and morbidity which urge the need for development of new therapeutic strategies …

Extremely low frequency magnetic fields (ELF‐MF) are common environmental agents that
are suspected to promote later stages of tumorigenesis, especially in brain‐derived …

Occupational and environmental causes of bronchiolar disorders are recognized on the
basis of case reports, case series, and, less commonly, epidemiologic investigations …

Methylglyoxal (MG), one of the uremic toxins, is a highly reactive alpha-dicarbonyl
compound. Recent clinical studies have demonstrated the close associations of cognitive …

Diabetic neuropathy (DN) is the most common diabetic complication. It is estimated diabetic
population will increase to 592 million by the year 2035. This is while at least 50–60% of all …

Background Glyoxalase I is a metalloenzyme of the glyoxalase pathway that plays a central
role in eliminating the toxic metabolite methyglyoxal. The protozoan parasite Leishmania …

In addition to its well-characterized role in the lens, αB-crystallin performs other functions.
Methylglyoxal (MGO) can alter the function of the basement membrane of retinal pigment …

Reactive oxygen species (ROS) play an important role as mediators of pulmonary damage
in mineral dust-induced diseases. Studies carried out to date have largely focused on silica …

Methylglyoxal (MGO), a cytotoxic metabolite, is produced from glycolysis. Elevated levels of
MGO are observed in a number of diabetic complications, including retinopathy …

Perinatal early nutritional disorders are critical for the developmental origins of health and
disease. Glycotoxins, or advanced glycation end-products, and their precursors such as the …