Universal features of Nsp1-mediated translational shutdown by coronaviruses
K Schubert, ED Karousis, I Ban, CP Lapointe… - Molecular cell, 2023 - cell.com
Summary Nonstructural protein 1 (Nsp1) produced by coronaviruses inhibits host protein
synthesis. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Nsp1 C …
synthesis. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Nsp1 C …
A SARS-CoV-2–host proximity interactome
P Samavarchi-Tehrani, H Abdouni, JDR Knight… - BioRxiv, 2020 - biorxiv.org
Viral replication is dependent on interactions between viral polypeptides and host proteins.
Identifying virus-host protein interactions can thus uncover unique opportunities for …
Identifying virus-host protein interactions can thus uncover unique opportunities for …
Structural basis for translation inhibition by MERS-CoV Nsp1 reveals a conserved mechanism for betacoronaviruses
All betacoronaviruses (β-CoVs) encode non-structural protein 1 (Nsp1), an essential
pathogenicity factor that potently restricts host gene expression. Among the β-CoV family …
pathogenicity factor that potently restricts host gene expression. Among the β-CoV family …
Insights into the inhibitory activity and mechanism of action of flavonoids from the stems and branches of Acer mono Maxim. against α-glucosidase via kinetic analysis …
Acer mono Maxim.(mono maple), a deciduous tree found in temperate regions, has been
reported to have a variety of pharmacological properties, including antioxidant …
reported to have a variety of pharmacological properties, including antioxidant …
Bases moleculares de la patogénesis de Covid-19 y estudios in silico de posibles tratamientos farmacológicos
E Lam-Cabanillas, A León-Risco… - Revista de la Facultad …, 2021 - scielo.org.pe
La COVID-19 es una enfermedad causada por el virus SARS-CoV-2, que representa una
grave amenaza para la salud mundial. El objetivo de este artículo es profundizar en la …
grave amenaza para la salud mundial. El objetivo de este artículo es profundizar en la …
Emerging mutations in Nsp1 of SARS-CoV-2 and their effect on the structural stability
The genome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) encodes 16
non-structural (Nsp) and 4 structural proteins. Among the Nsps, Nsp1 inhibits host gene …
non-structural (Nsp) and 4 structural proteins. Among the Nsps, Nsp1 inhibits host gene …
Distinct evolutionary trajectories of SARS-CoV-2-interacting proteins in bats and primates identify important host determinants of COVID-19
The coronavirus disease 19 (COVID-19) pandemic is caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), a coronavirus that spilled over from the bat …
syndrome coronavirus 2 (SARS-CoV-2), a coronavirus that spilled over from the bat …
Characterizing genomic variants and mutations in SARS-CoV-2 proteins from Indian isolates
SARS-CoV-2 is mutating and creating divergent variants by altering the composition of
essential constituent proteins. Pharmacologically, it is crucial to understand the diverse …
essential constituent proteins. Pharmacologically, it is crucial to understand the diverse …
A study on non-synonymous mutational patterns in structural proteins of SARS-CoV-2
SARS-CoV-2 is mutating and creating divergent variants across the world. An in-depth
investigation of the amino acid substitutions in the genomic signature of SARS-CoV-2 …
investigation of the amino acid substitutions in the genomic signature of SARS-CoV-2 …
Recent trends in next generation immunoinformatics harnessed for universal coronavirus vaccine design
CP Lim, BH Kok, HT Lim, C Chuah… - … and Global Health, 2023 - Taylor & Francis
The ongoing pandemic of coronavirus disease 2019 (COVID-19), caused by the severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has globally devastated public …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has globally devastated public …