Microvascular alteration in COVID-19 documented by nailfold capillaroscopy

L Mondini, P Confalonieri, R Pozzan, L Ruggero… - Diagnostics, 2023 - mdpi.com
COVID-19 is a multisystemic disease that mainly affects and causes dysregulation of the
endothelium, causing systemic manifestations. A nailfold video capillaroscopy is a safe …

The Ways of the Virus: Interactions of Platelets and Red Blood Cells with SARS-CoV-2, and Their Potential Pathophysiological Significance in COVID-19

MA Panteleev, AN Sveshnikova… - International Journal of …, 2023 - mdpi.com
The hematological effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) are important in COVID-19 pathophysiology. However, the interactions of SARS-CoV-2 …

Sequential multi-omics analysis identifies clinical phenotypes and predictive biomarkers for long COVID

K Wang, M Khoramjoo, K Srinivasan, PMK Gordon… - Cell Reports …, 2023 - cell.com
The post-acute sequelae of COVID-19 (PASC), also known as long COVID, is often
associated with debilitating symptoms and adverse multisystem consequences. We obtain …

SARS-CoV-2 Omicron variant infection affects blood platelets, a comparative analysis with Delta variant

C Garcia, B Compagnon, A Ribes, S Voisin… - Frontiers in …, 2023 - frontiersin.org
Introduction In November 2021, the SARS-CoV-2 Omicron variant of concern has emerged
and is currently dominating the COVID-19 pandemic over the world. Omicron displays a …

Short Survey on the Protein Modifications in Plasma during SARS-CoV-2 Infection

A Gęgotek, N Zarkovic, B Orehovec… - International journal of …, 2023 - mdpi.com
Although the COVID-19 pandemic has ended, it is important to understand the pathology of
severe SARS-CoV-2 infection associated with respiratory failure and high mortality. The …

Differential platelet activation through an interaction with spike proteins of different SARS-CoV-2 variants

Z Sevilya, A Kuzmina, M Cipok, V Hershkovitz… - Journal of Thrombosis …, 2023 - Springer
COVID-19 disease is associated with an increased risk of thrombotic complications, which
contribute to high short-term mortality. Patients with COVID-19 demonstrate enhanced …

Novel mechanism of the COVID-19 associated coagulopathy (CAC) and vascular thromboembolism

M Singh, S Pushpakumar, Y Zheng, I Smolenkova… - npj Viruses, 2023 - nature.com
Previous studies from our laboratory revealed that SARS-CoV-2 spike protein (SP)
administration to a genetically engineered model expressing the human angiotensin …

SARS-CoV-2 infection modifies the transcriptome of the megakaryocytes in the bone marrow

I Allaeys, G Lemaire, M Leclercq, E Lacasse… - Blood …, 2024 - ashpublications.org
Megakaryocytes (MKs), integral to platelet production, predominantly reside in the bone
marrow (BM) and undergo regulated fragmentation within sinusoid vessels to release …

Understanding COVID-19-associated endothelial dysfunction: role of PIEZO1 as a potential therapeutic target

X Zhang, J Liu, X Deng, L Bo - Frontiers in Immunology, 2024 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Due to its high infectivity, the …

Does SARS-CoV-2 infect platelets?

S Subramaniam, N Mohiuddin, A Jose - Frontiers in Immunology, 2024 - frontiersin.org
COVID-19 is characterized by dysregulated thrombo-inflammatory responses and
coagulation, leading to an increased risk of mortality in affected patients (1–3). Platelets play …