Hippocampal contributions to social and cognitive deficits in autism spectrum disorder

SM Banker, X Gu, D Schiller, JH Foss-Feig - Trends in neurosciences, 2021 - cell.com
Autism spectrum disorder (ASD) is characterized by hallmark impairments in social
functioning. Nevertheless, nonsocial cognition, including hippocampus-dependent spatial …

Brain mechanisms supporting flexible cognition and behavior in adolescents with autism spectrum disorder

LQ Uddin - Biological Psychiatry, 2021 - Elsevier
Cognitive flexibility enables appropriate responses to a changing environment and is
associated with positive life outcomes. Adolescence, with its increased focus on transitioning …

Reduced hippocampal functional connectivity during episodic memory retrieval in autism

RA Cooper, FR Richter, PM Bays… - Cerebral …, 2017 - academic.oup.com
Increasing recent research has sought to understand the recollection impairments
experienced by individuals with autism spectrum disorder (ASD). Here, we tested whether …

[HTML][HTML] Exploring the neurocognitive basis of episodic recollection in autism

RA Cooper, JS Simons - Psychonomic bulletin & review, 2019 - Springer
Increasing evidence indicates that the subjective experience of recollection is diminished in
autism spectrum disorder (ASD) compared to neurotypical individuals. The neurocognitive …

Related to anxiety: Arbitrarily applicable relational responding and experimental psychopathology research on fear and avoidance

S Dymond, M Bennett, S Boyle, B Roche… - Perspectives on Behavior …, 2018 - Springer
Humans have an unparalleled ability to engage in arbitrarily applicable relational
responding (AARR). One of the consequences of this ability to spontaneously combine and …

Cognitive control and episodic memory in adolescents with autism spectrum disorders

M Solomon, JB McCauley, AM Iosif, CS Carter… - Neuropsychologia, 2016 - Elsevier
Introduction To further investigate manifestations of episodic memory impairments in
adolescents, we examined the role of encoding on recognition of stimuli in conditions …

Compensatory hippocampal recruitment supports preserved episodic memory in autism spectrum disorder

J Hogeveen, MK Krug, RM Geddert, JD Ragland… - Biological Psychiatry …, 2020 - Elsevier
Background The degree to which individuals with autism spectrum disorder (ASD) evidence
impairments in episodic memory relative to their typically developing (TD) counterparts …

A potential mechanistic role for neuroinflammation in reward processing impairments in autism spectrum disorder

RK Greene, E Walsh, MG Mosner, GS Dichter - Biological psychology, 2019 - Elsevier
Accumulating evidence suggests that autism spectrum disorder (ASD) may be
conceptualized within a framework of reward processing impairments. The Social Motivation …

[HTML][HTML] Insights into the structure and function of the hippocampus: implications for the pathophysiology and treatment of autism spectrum disorder

J Long, H Li, Y Liu, X Liao, Z Tang, K Han… - Frontiers in …, 2024 - frontiersin.org
The hippocampus is one of the brain areas affected by autism spectrum disorder (ASD).
Individuals with ASD typically have impairments in hippocampus-dependent learning …

Disruption of the autism gene and chromatin regulator KDM5A alters hippocampal cell identity

L El Hayek, D DeVries, A Gogate, A Aiken, K Kaur… - Science …, 2023 - science.org
Chromatin regulation plays a pivotal role in establishing and maintaining cellular identity
and is one of the top pathways disrupted in autism spectrum disorder (ASD). The …