Clinical trials typically analyze multiple endpoints for signals of efficacy. To improve signal
detection for treatment effects using the high-dimensional data collected in trials, we …

We make use of expected information gain to quantify the amount of knowledge obtained
from measurements in a population. In the first application, we compared the expected …

Multidimensional psychometric functions can typically be estimated nonparametrically for
greater accuracy or parametrically for greater efficiency. By recasting the estimation problem …

The speed–accuracy tradeoff (SAT) often makes psychophysical data difficult to interpret.
Accordingly, the SAT experimental procedure and model were proposed for an integrated …

The external noise paradigm and perceptual template model (PTM) have successfully been
applied to characterize observer properties and mechanisms of observer state changes (eg …

Perceptual learning is a multifaceted process, encompassing general learning, between-
session forgetting or consolidation, and within-session fast relearning and deterioration. The …

The learning curve serves as a crucial metric for assessing human performance in
perceptual learning. It may encompass various component processes, including general …

Recent advances in nonparametric Contrast Sensitivity Function (CSF) estimation have
yielded a new tradeoff between accuracy and efficiency not available to classical parametric …

The visual world is processed with a great degree of non-uniformity across eccentricity and
around polar angle locations. Contrast sensitivity, a fundamental visual dimension …

METHOD: Informed consent was taken from each patient after a verbal and written
explanation of the nature and consequences of the study. A performa was filled at the time of …