Abstract Development and Phase 3 testing of the most advanced malaria vaccine, RTS,
S/AS01, indicates that malaria vaccine R&D is moving into a new phase. Field trials of …

Rational selection of individual adjuvants can often be made on the basis of innate
molecular interactions of the foreign molecules with pattern recognition receptors such as …

Plasmodium falciparum reticulocyte binding-like homologous protein 5 (PfRH5) is an
essential merozoite ligand that binds with its erythrocyte receptor, basigin. PfRH5 is an …

Resistance to commercially available antimalarial drugs is a public health problem. Since
the end of the last century, no new antimalarial drugs have been introduced into clinical …

Human infection with Plasmodium parasites remains a serious global health crisis, leading
to more than 600,000 deaths annually. Currently, no licensed vaccine is available to …

Malaria vaccines are considered amongst the most important modalities for potential
elimination of malaria disease and transmission. Research and development in this field has …

This chapter applies the framework of public goods to knowledge. It shows that knowledge
has some characteristics of public good, such as being non‐rival in consumption and in the …

In this study, a novel mathematical model is developed to investigate the effectiveness of
imperfect human vaccination against malaria. The model is a system of ordinary differential …

Ripley Ballou shakes the hand of Mr Thomas, a community elder in Mligotini village,
Bagamoyo, Tanzania. Also sitting is Dr Omar Juma, who at the time was director of the …

Mathematical models to study the dynamics of malaria continue to be developed and
upgraded on the parasite component, which is the causative agent for malaria; on the …