Blood biomarkers for stroke diagnosis and management

J Kamtchum-Tatuene, GC Jickling - Neuromolecular medicine, 2019 - Springer
Biomarkers are objective indicators used to assess normal or pathological processes,
evaluate responses to treatment and predict outcomes. Many blood biomarkers already …

Blood biomarkers in ischemic stroke: potential role and challenges in clinical practice and research

K Makris, A Haliassos, M Chondrogianni… - Critical reviews in …, 2018 - Taylor & Francis
Fast and accurate diagnosis of stroke is crucial for the immediate application of the right
therapy to patients. However, rapid diagnosis is still a challenge since an ischemic stroke …

Genetics of ischemic stroke, stroke-related risk factors, stroke precursors and treatments

D Della-Morte, F Guadagni, R Palmirotta… - …, 2012 - Taylor & Francis
Stroke remains a leading cause of death worldwide and the first cause of disability in the
western world. Ischemic stroke (IS) accounts for almost 80% of the total cases of strokes and …

How to make better use of thrombolytic therapy in acute ischemic stroke

GA Donnan, SM Davis, MW Parsons, H Ma… - Nature Reviews …, 2011 - nature.com
Around 15 years have now elapsed since thrombolysis was first shown to be effective for
treating acute ischemic stroke, but therapeutic uptake has been modest. As outlined in this …

The trends in nanomaterial-based biosensors for detecting critical biomarkers in stroke

S Dolati, J Soleymani, SK Shakouri, A Mobed - Clinica chimica acta, 2021 - Elsevier
Acute ischemic stroke (AIS), is the second global cause of death after cardiovascular
diseases, accounts for 80–85% of cerebrovascular disease. Stroke diagnosis could be …

Serum microRNA-based risk prediction for stroke

T Sonoda, J Matsuzaki, Y Yamamoto, T Sakurai, Y Aoki… - Stroke, 2019 - Am Heart Assoc
Background and Purpose—Numerous studies have shown that circulating microRNAs
(miRNAs) can be used as noninvasive biomarkers of various diseases. This study aimed to …

The relationship between early concentrations of 25 blood proteins and cerebral white matter injury in preterm newborns: the ELGAN study

A Leviton, K Kuban, TM O'Shea, N Paneth… - The Journal of …, 2011 - Elsevier
OBJECTIVE: To evaluate whether concentrations of inflammation-related proteins are
elevated in the blood of preterm newborns who develop cerebral white matter damage …

Evolving role of biomarkers in acute cerebrovascular disease

DN Kernagis, DT Laskowitz - Annals of neurology, 2012 - Wiley Online Library
The development of a clinically validated biomarker of acute cerebral ischemia would have
the potential to facilitate the use of time‐sensitive reperfusion strategies, allow for …

Blood protein biomarkers as diagnostic tool for ischemic stroke: a systematic review

T Monbailliu, J Goossens… - Biomarkers in …, 2017 - Taylor & Francis
Aim: This systematic review provides a summary of the blood protein biomarkers that have
been studied for the diagnosis of acute ischemic stroke. Materials & methods: An extensive …

Early postnatal blood concentrations of inflammation-related proteins and microcephaly two years later in infants born before the 28th post-menstrual week

A Leviton, KCK Kuban, EN Allred, RN Fichorova… - Early human …, 2011 - Elsevier
BACKGROUND: To evaluate if concentrations of inflammation-related proteins were
elevated in early postnatal blood specimens of preterm newborns who two years later had a …