The tubulin code and its role in controlling microtubule properties and functions

C Janke, MM Magiera - Nature Reviews Molecular Cell Biology, 2020 - nature.com
Microtubules are core components of the eukaryotic cytoskeleton with essential roles in cell
division, shaping, motility and intracellular transport. Despite their functional heterogeneity …

[HTML][HTML] The tubulin code in microtubule dynamics and information encoding

A Roll-Mecak - Developmental cell, 2020 - cell.com
Microtubules are non-covalent mesoscale polymers central to the eukaryotic cytoskeleton.
Microtubule structure, dynamics, and mechanics are modulated by a cell's choice of tubulin …

[HTML][HTML] The tubulin code, from molecules to health and disease

ED McKenna, SL Sarbanes… - Annual Review of …, 2023 - annualreviews.org
Microtubules are essential dynamic polymers composed of α/β-tubulin heterodimers. They
support intracellular trafficking, cell division, cellular motility, and other essential cellular …

Posttranslational modification of microtubules by the MATCAP detyrosinase

L Landskron, J Bak, A Adamopoulos, K Kaplani… - Science, 2022 - science.org
The detyrosination-tyrosination cycle involves the removal and religation of the C-terminal
tyrosine of α-tubulin and is implicated in cognitive, cardiac, and mitotic defects. The …

[HTML][HTML] The variation and evolution of complete human centromeres

GA Logsdon, AN Rozanski, F Ryabov, T Potapova… - Nature, 2024 - nature.com
Human centromeres have been traditionally very difficult to sequence and assemble owing
to their repetitive nature and large size. As a result, patterns of human centromeric variation …

Principles and mechanisms of asymmetric cell division

B Sunchu, C Cabernard - Development, 2020 - journals.biologists.com
Asymmetric cell division (ACD) is an evolutionarily conserved mechanism used by
prokaryotes and eukaryotes alike to control cell fate and generate cell diversity. A detailed …

[HTML][HTML] Tubulin posttranslational modifications and emerging links to human disease

MM Magiera, P Singh, S Gadadhar, C Janke - Cell, 2018 - cell.com
Tubulin posttranslational modifications are currently emerging as important regulators of the
microtubule cytoskeleton and thus have a strong potential to be implicated in a number of …

[图书][B] Population genetics and microevolutionary theory

AR Templeton - 2021 - books.google.com
Population Genetics and Microevolutionary Theory Explore the fundamentals of the
biological implications of population genetic theory In the newly revised Second Edition of …

Meiosis: the chromosomal foundation of reproduction

E Bolcun-Filas, MA Handel - Biology of reproduction, 2018 - academic.oup.com
Meiosis is the chromosomal foundation of reproduction, with errors in this important process
leading to aneuploidy and/or infertility. In this review celebrating the 50th anniversary of the …

Meiotic drive mechanisms: lessons from Drosophila

C Courret, CH Chang, KHC Wei… - … of the Royal …, 2019 - royalsocietypublishing.org
Meiotic drivers are selfish genetic elements that bias their transmission into gametes, often
to the detriment of the rest of the genome. The resulting intragenomic conflicts triggered by …