Family history of rheumatoid arthritis (RA) is a proxy for an individual's genetic and, in part,
environmental risk of developing RA, and is a well-recognized predictor of disease onset …

The gut microbiota has a crucial effect on human health and physiology. Hypothyroid
Hashimoto's thyroiditis (HT) is an autoimmune disorder manifested with environmental and …

The major histocompatibility complex system is the most polymorphic gene cluster of the
mammal genome. In humans, this is a genomic locus known as the human leukocyte …

The human microbiome consists of all microorganisms occupying the skin, mucous
membranes and intestinal tract of the human body. The contact of the mucosal immune …

IL-36 cytokines have recently emerged as mediators of inflammation in autoimmune
conditions including psoriasis vulgaris (PsV) and generalized pustular psoriasis (GPP). This …

Autoimmune diseases (ADs) represent a heterogeneous group of disorders that affect
specific target organs or multiple organ systems. These conditions share common …

Abstract “Rhupus” or “rhupus syndrome” is a poorly described and underdiagnosed disease
in which features of both rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) …

Immune-mediated inflammatory diseases (IMIDs) are characterized by dysregulation of the
normal immune response, which leads to inflammation. Together, they account for a high …

Human T-lymphotropic virus type-1 (HTLV-1) infection is associated with adult T-cell
leukemia/lymphoma (ATL). Tropical spastic paraparesis/HTLV-1-associated myelopathy …

Myasthenia Gravis (MG) is a paradigm of organ-specific autoimmune disease (AID). It is
mediated by antibodies that target the neuromuscular junction. The purpose of this review is …